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228419-13-4

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228419-13-4 Usage

General Description

3-Benzyloxybenzhydrazide is an organic compound with the molecular formula C14H14N2O. It is a benzhydrazide derivative and has a benzyl ether functional group. 3-Benzyloxybenzhydrazide is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds due to its versatile reactivity and ability to participate in a wide range of chemical reactions. It is also used as a reagent in organic and medicinal chemistry research. This chemical has potential applications in drug discovery and development, as well as in the synthesis of biologically active molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 228419-13-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,8,4,1 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 228419-13:
(8*2)+(7*2)+(6*8)+(5*4)+(4*1)+(3*9)+(2*1)+(1*3)=134
134 % 10 = 4
So 228419-13-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2O2/c15-16-14(17)12-7-4-8-13(9-12)18-10-11-5-2-1-3-6-11/h1-9H,10,15H2,(H,16,17)

228419-13-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Benzyloxybenzhydrazide

1.2 Other means of identification

Product number -
Other names 3-BENZYLOXYBENZHYDRAZIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:228419-13-4 SDS

228419-13-4Relevant articles and documents

Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents

Bi, Fangchao,Ji, Shengli,Venter, Henrietta,Liu, Jingru,Semple, Susan J.,Ma, Shutao

, p. 884 - 891 (2018/02/15)

3-Methoxybenzamide (3-MBA) derivatives have been identified as novel class of potent antibacterial agents targeting the bacterial cell division protein FtsZ. As one of isosteres for the amide group, 1,2,3-triazole can mimic the topological and electronic features of the amide, which has gained increasing attention in drug discovery. Based on these considerations, we prepared a series of 1H-1,2,3-triazole-containing 3-MBA analogues via isosteric replacement of the terminal amide with triazole, which had increased antibacterial activity. This study demonstrated the possibility of developing the 1H-1,2,3-triazole group as a terminal amide-mimetic element which was capable of both keeping and modulating amide-related bioactivity. Surprisingly, a different action mode of these new 1H-1,2,3-triazole-containing analogues was observed, which could open new opportunities for the development of antibacterial agents.

Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues

Khan, Khalid Mohammad,Rasheed, Maimona,Ullah, Zia,Hayat, Safdar,Kaukab, Farhana,Choudhary, M. Iqbal,Ur-Rahman, Atta,Perveen, Shahnaz

, p. 1381 - 1387 (2007/10/03)

Twenty-one hydrazides were synthesized by treating different esters with hydrazine hydrate. Substituted hydrazides were obtained by treating hydrazides with alkyl/aryl/acyl halides. Some of these compounds exhibit potential in vitro leishmanicidal activity. The structures of all the synthesized compounds were confirmed by spectroscopic analysis.

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