22876-15-9

Usage

Uses

Used in Pharmaceutical Synthesis:
5-METHYL-1,3-BENZOXAZOL-2(3H)-ONE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Organic Compound Synthesis:
5-MBO is used as a building block in the synthesis of various organic compounds, leveraging its structural properties to create a wide range of chemical products.
Used in Fluorescent Probes and Dyes:
5-METHYL-1,3-BENZOXAZOL-2(3H)-ONE is used as a fluorescent component in the development of probes and dyes due to its strong fluorescence properties, which are valuable in research and analytical applications.
Used in Materials Science:
In the field of materials science, 5-MBO is used as a component in the development of new materials, potentially contributing to advancements in areas such as polymers and composites.
Used in Biochemistry:
5-METHYL-1,3-BENZOXAZOL-2(3H)-ONE is utilized in biochemical research for its potential role in the study of biological processes and the development of bioactive molecules.

InChI:InChI=1/C8H7NO2/c1-5-2-3-7-6(4-5)9-8(10)11-7/h2-4H,1H3,(H,9,10)

Upstream product

• 64037-15-6 5-methylbenzo[d]oxazol-2-amine 
• 28115-86-8 3-methylbenzoyl isothiocyanate 
• 1435-71-8 4-methyl-2-(2-nitrophenylazo)phenol 
• 22876-22-8 4-methyl-1,3-benzoaxazolidine-2-thione 
• 108-95-2 phenol 
• 100-66-3 methoxybenzene 
• 16794-67-5 p-chlorobenzoyl isothiocyanate 

Downstream Products

• 6265-06-1 2-Amino-4-methyl-5-nitro-phenol 
• 22876-22-8 4-methyl-1,3-benzoaxazolidine-2-thione 
• 863716-89-6 6-(2-chloro-benzoyl)-5-methyl-3H-benzooxazol-2-one 
• 863716-90-9 6-(4-chloro-benzoyl)-5-methyl-3H-benzooxazol-2-one 
• 10378-06-0 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline 

Relevant academic research and scientific papers

Regioselective thiolation of arenes and heteroarenes: C-H functionalization strategy for C-S bond formation

A facile transition-metal-free oxidative cross-dehydrogenative coupling reaction involving selective formation of a C-S bond leading to the synthesis of arylthiobenzoxazoles, heteroarylthiobenzoxazoles, and arylthiobenzothiazoles has been described. This highly regioselective C-H functionalization reaction with electron-rich aromatic systems including heteroaromatics is achieved by reversing the reactivity of sulfur in the presence of a suitable oxidant and strong acid. (Chemical Equation Presented).

SYNTHESIS OF SOME BENZOTRIAZOLES BY DEOXYGENATION OF o-NITROPHENYLAZO COMPOUNDS BY TERTIARY AMINES AND CO

NEt3 promotes the deoxygenation of specific ortho-nitrophenylazo compounds affording benzotriazoles in good yields and selectivities. The role of the amine is examined in the deoxygenation process with CO as the final oxygen acceptor.

One Pot Synthesis of 4-Arylbenzoxazolo-s-triazine-2-thiones

The reaction of 2-aminobenzoxazoles (1a-b) with aroyl isothiocyanates in acetone gave 4-arylbenzoxazolo-s-triazine-2-thiones (3a-g), aroylthioureas (5a-e) and 2-benzoxazolones (6a-b).A reasonable pathway for the formation of 3, 5 and 6 from 1 has been suggested.