229153-04-2

Upstream product

• 288-88-0 1,2,4-Triazole 
• 229153-29-1 2-[difluoro(ethylthio)methyl]-2-(2,4-difluorophenyl)oxirane 
• 102429-07-2 2-bromo-2',4'-difluoroacetophenone 
• 229153-25-7 2-(ethylthio)-2,2,2',4'-tetrafluoroacetophenone 
• 229153-21-3 2',4'-difluoro-α-(ethylthio)acetophenone 

Downstream Products

• 229153-10-0 (-)-2-(2,4-difluorophenyl)-1-(ethylsulfonyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)-2-propanol 
• 229153-08-6 1-[2-(2,4-difluorophenyl)-3-(ethylthio)-3,3-difluoro-2-methoxypropyl]-1H-1,2,4-triazole 
• 229153-09-7 1-[2-(benzyloxy)-2-(2,4-difluorophenyl)-3-(ethylthio)-3,3-difluoropropyl]-1H-1,2,4-triazole 

Relevant academic research and scientific papers

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety

New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus