229153-10-0

Upstream product

• 229153-29-1 2-[difluoro(ethylthio)methyl]-2-(2,4-difluorophenyl)oxirane 
• 229153-25-7 2-(ethylthio)-2,2,2',4'-tetrafluoroacetophenone 
• 229153-21-3 2',4'-difluoro-α-(ethylthio)acetophenone 
• 102429-07-2 2-bromo-2',4'-difluoroacetophenone 
• 229153-04-2 2-(2,4-difluorophenyl)-1-(ethylthio)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)-2-propanol 

Relevant academic research and scientific papers

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety

New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus

Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient

Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a h