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2',4'-difluoro-α-(ethylthio)acetophenone is a chemical compound characterized by the molecular formula C10H9F2OS. It is a white or off-white solid that serves as a crucial intermediate in the synthesis of pharmaceuticals and agrochemicals. 2',4'-difluoro-α-(ethylthio)acetophenone features a fluoro-substituted phenyl ring, a ketone group, and an ethylthio side chain, which contribute to its reactivity and make it a versatile building block for the preparation of various chemical compounds.

229153-21-3

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229153-21-3 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2',4'-difluoro-α-(ethylthio)acetophenone is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and reactivity allow for the development of new and effective compounds for medical and agricultural applications.
Used as a Flavoring Agent in the Food Industry:
2',4'-difluoro-α-(ethylthio)acetophenone is also employed as a flavoring agent in the food industry, adding unique taste profiles to various food products. Its use in this industry highlights its versatility beyond pharmaceutical and agrochemical applications.
Safety Precautions:
It is important to handle 2',4'-difluoro-α-(ethylthio)acetophenone with caution due to its potential harmful effects if ingested or inhaled. Additionally, it can cause skin and eye irritation, necessitating proper safety measures during its use and storage.

Check Digit Verification of cas no

The CAS Registry Mumber 229153-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,9,1,5 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 229153-21:
(8*2)+(7*2)+(6*9)+(5*1)+(4*5)+(3*3)+(2*2)+(1*1)=123
123 % 10 = 3
So 229153-21-3 is a valid CAS Registry Number.

229153-21-3Relevant academic research and scientific papers

α, α-gem-difluorination of α-(alkylthio)acetophenone derivatives with N-Fluoropyridinium salts

Takeda, Sunao,Kaneko, Yasushi,Eto, Hiromichi,Tokizawa, Minoru,Sato, Susumu,Yoshida, Kouiti,Namiki, Setsuo,Ogawa, Masaki

, p. 1097 - 1100 (2000)

The α, α-gem-difluorination of 2',4'-difluoro- α(methylthio)acetophenone (1a) with N-fluoropyridinium salts gave 2',4',α-tetrafluoro-α-(methylthio)acetophenone (3a). This reaction was accelerated by the addition of zinc chloride, zinc bromide or anhydrous iron(III) chloride, and higher yields than the reaction without additives were obtained. The gem- difluorination reaction using FP-T300 in the presence of zinc bromide was applicable to other α-(alkylthio)acetophenone derivatives (1).

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety

Eto,Kaneko,Takeda,Tokizawa,Sato,Yoshida,Namiki,Ogawa,Maebashi,Ishida,Matsumoto,Asaoka

, p. 173 - 182 (2007/10/03)

New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus

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