22927-18-0Relevant academic research and scientific papers
Regioselective hydroformylation of allylic alcohols
Lightburn, Thomas E.,De Paolis, Omar A.,Cheng, Ka H.,Tan, Kian L.
supporting information; experimental part, p. 2686 - 2689 (2011/06/28)
A highly regioselective hydroformylation of allylic alcohols is reported toward the synthesis of β-hydroxy-acid and aldehyde products. The selectivity is achieved through the use of a ligand that reversibly binds to alcohols in situ, allowing for a directed hydroformylation to occur. The application to trisubstituted olefins was also demonstrated, which yields a single diastereomer product consistent with a stereospecific addition of CO and hydrogen.
SYNTHESIS OF 1-SUBSTITUTED (S)-4-ACETOXY-1-PENTEN-3-ONES USING (S)-LACTIC ACID AS A CHIRAL SOURCE AND THEIR SYNTHETIC REACTIONS
Hiyama, Tamejiro,Kobayashi, Kumi,Fujita, Makoto
, p. 4959 - 4962 (2007/10/02)
Ylide reaction of (S)-3-acetoxy-1-triphenylphosphoranylidene-2-butanone, derived from (S)-lactic acid, with aldehydes gives 1-substituted (S)-4-acetoxy-1-penten-3-one derivatives, which are shown to be transformed into useful chiral compouds by stereosele
