229307-67-9

Upstream product

• 200726-79-0 4-hydroxy-8-methyl-7-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-1-benzopyran-2-one 
• 200726-78-9 1-[2-hydroxy-3-methyl-4-[(tetrahydro-2H-pyran-2-yl)oxy]]phenyl ethanone 
• 10139-84-1 1-(2,4-dihydroxy-3-methylphenyl)ethanone 
• 229308-91-2 4-benzhydryloxy-8-methyl-7-(tetrahydro-pyran-2-yloxy)-chromen-2-one 

Downstream Products

• 229308-40-1 4-Benzhydryloxy-7-((3aR,4R,6S,7R,7aR)-6-ethyl-7-methoxy-6-methyl-2-oxo-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yloxy)-8-methyl-chromen-2-one 
• 297754-70-2 C₃₄H₃₂O₉ 
• 245729-78-6 5-methyl-1H-pyrrole-2-carboxylic acid 6-(4-benzhydryloxy-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-5-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester 
• 229307-70-4 7-[[6-Deoxy-5-C-methyl-4-O-methyl-2-O-(tetrahydro-2H-pyran-2-yl)-3-O-(triethylsilyl)-α-L-lyxo-hexopyranosyl]oxy]-4-(diphenylmethoxy)-8-methyl-2H-1-benzopyran-2-one 
• 229307-69-1 4-Benzhydryloxy-7-((2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-8-methyl-chromen-2-one 
• 229307-68-0 7-[[6-Deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-(diphenylmethoxy)-8-methyl-2H-1-benzopyran-2-one 

Relevant academic research and scientific papers

Ribose-substituted aromatic amides, method for the production and use thereof as medicaments

Compounds of formula (I); wherein R1=alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R2=hydrogen or halogen; R3=hydrogen, alkyl or halogen; R4=NHR′ or N

Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B

The design, synthesis, and in vitro biological activity of a series of novel coumarin inhibitors of gyrase B is presented. Replacement of the 3- acylamino residue (3-NHCOR) of coumarin drags with reversed isosteres C(=O)R, C(=N-OR)R', COOR, CONHR and CONH