229308-74-1Relevant academic research and scientific papers
2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents
Francesconi, Iris,Wilson, W. David,Tanious, Farial A.,Hall, James E.,Bender, Brendan C.,Tidwell, Richard R.,McCurdy, Donald,Boykin, David W.
, p. 2260 - 2265 (2007/10/03)
Dicationic 2,4-bis(4-amidinophenyl)furans 5-10 and 2,4-bis(4- amidinophenyl)-3,5-dimethylfurans 14 and 15 have been synthesized. Thermal melting studies revealed high binding affinity of the compounds to poly(dA- dT) and to the duplex oligomer d(CGCGAATTC
2,4-bis[(4-amidino)phenyl]furans as anti-Pneumocystis carinii agents
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, (2008/06/13)
Compounds according to the formula: STR1 wherein: R1 and R2 are each independently selected from the group consisting of H, loweralkyl, aryl, alkylaryl, aminoalkyl, aminoaryl, halogen, oxyalkyl, oxyaryl, or oxyarylalkyl; R3/sub
