229308-74-1Relevant articles and documents
2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents
Francesconi, Iris,Wilson, W. David,Tanious, Farial A.,Hall, James E.,Bender, Brendan C.,Tidwell, Richard R.,McCurdy, Donald,Boykin, David W.
, p. 2260 - 2265 (2007/10/03)
Dicationic 2,4-bis(4-amidinophenyl)furans 5-10 and 2,4-bis(4- amidinophenyl)-3,5-dimethylfurans 14 and 15 have been synthesized. Thermal melting studies revealed high binding affinity of the compounds to poly(dA- dT) and to the duplex oligomer d(CGCGAATTC