22936-83-0

Basic information

• Product Name: 1-METHYL-1-CYCLOPROPANAMINE
• Synonyms: 1-METHYL-1-CYCLOPROPANAMINE;1-METHYLCYCLOPROPANAMINE;(1-methylcyclopropyl)amine(SALTDATA: HCl);1-Methyl-1-cyclopropanaMine hydrochloride;1-Amino-1-methylcyclopropane;1-Methylcyclopropan-1-amine;1-Methylcyclopropylamine
• CAS NO: 22936-83-0
• Molecular Formula: C₄H₉N
• Molecular Weight: 71.121
• Mol File: 22936-83-0.mol

Chemical Properties

• Melting Point: 61℃
• Boiling Point: 60.895 °C at 760 mmHg
• Flash Point: -31℃
• Appearance: /
• Density: 0.897
• Vapor Pressure: 189.47mmHg at 25°C
• Refractive Index: 1.4130
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.10±0.20(Predicted)
• CAS DataBase Reference: 1-METHYL-1-CYCLOPROPANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-1-CYCLOPROPANAMINE(22936-83-0)
• EPA Substance Registry System: 1-METHYL-1-CYCLOPROPANAMINE(22936-83-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 22936-83-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-METHYL-1-CYCLOPROPANAMINE is used as a synthetic intermediate for the development of various pharmaceuticals, leveraging its reactivity and structural properties to facilitate the creation of new medicinal compounds.
Used in Agricultural Chemicals:
In the agricultural sector, 1-METHYL-1-CYCLOPROPANAMINE is utilized as a key component in the production of pesticides and other agrochemicals, contributing to the development of effective solutions for crop protection and enhancement of agricultural yields.

InChI:InChI=1/C4H9N/c1-4(5)2-3-4/h2-3,5H2,1H3

Upstream product

• 88887-87-0 1-methylcyclopropylamine hydrochloride 

Downstream Products

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• 75-05-8 acetonitrile 
• 1080572-33-3 3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methyl-N-(1-methylcyclopropyl)benzamide 
• 1021537-49-4 2-{2-[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}-N-(1-methylcyclopropyl)benzamide 
• 1449668-20-5 4-(3-ethyl-4-(methyl(1-methyl-1H-imidazo[4,5-c]pyridin-6-yl)amino)phenyl)-N-(1-methylcyclopropyl)-5,6-dihydropyridine-1(2H)-carboxamide 
• 1572510-67-8 C₁₈H₁₉FN₂O₃S 

Relevant articles and documents

Deamination Reactions, 44. Decomposition of 1-Alkylcyclopropanediazonium Ions

1-Methyl- (17), 1,2-dimethyl- (41, 44), 1-propyl- (64), 1-(1-methylethyl)cyclopropanediazonium ions (80), and -1-diazonium ions (93) have been generated by alkaline cleavage of the analogous nitrosocarbamates in methanol.Cyclopropyl-allyl transformation and nucleophilic displacement were the only reactions of 17, 41, 44, and 93 while elimination and 1,2-shifts of an α-hydrogen compete increasingly with 64 and 80.The stereochemistry of ring cleavage and nucleophilic displacement has been explored, using 2-D labels in the case of 17 and 93.Cyclopropanediazonium ions (1) and 41 react stereospecifically, 17 and 44 are moderately stereoselective (ca. 85:15), and 93 is entirely unselective.The data indicate a gradual changeover from concerted to stepwise mechanisms.Appreciable stabilization of the positive charge is required to reach the SN1 extreme.