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23053-35-2

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23053-35-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 23053-35-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,0,5 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23053-35:
(7*2)+(6*3)+(5*0)+(4*5)+(3*3)+(2*3)+(1*5)=72
72 % 10 = 2
So 23053-35-2 is a valid CAS Registry Number.

23053-35-2Relevant articles and documents

Small molecule inhibitors of plasma kallikrein

Young, Wendy B.,Rai, Roopa,Shrader, William D.,Burgess-Henry, Jana,Hu, Huiyong,Elrod, Kyle C.,Sprengeler, Paul A.,Katz, Bradley A.,Sukbuntherng, Juthamas,Mordenti, Joyce

, p. 2034 - 2036 (2007/10/03)

Plasma kallikrein is a serine protease that is involved in pathways of inflammation, complement fixation, coagulation, and fibrinolysis. Herein, we describe the SAR and structural binding modes of a series of inhibitors of plasma kallikrein as well as the

Factor VIIa inhibitors: Improved pharmacokinetic parameters

Kolesnikov, Aleksandr,Rai, Roopa,Young, Wendy B.,Mordenti, Joyce,Liu, Liang,Torkelson, Steven,Shrader, William D.,Leahy, Ellen M.,Hu, Huiyong,Gjerstad, Erik,Janc, James,Katz, Bradley A.,Sprengeler, Paul A.

, p. 2243 - 2246 (2007/10/03)

Efforts to improve the potency and pharmacokinetic properties of small molecule factor VIIa inhibitors are described. Small structural modifications to existing leads allow the modulation of half-life and clearance, potentially making these compounds suitable candidates for drug development.

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