17315-86-5Relevant academic research and scientific papers
Green and selective toluene oxidation–Knoevenagel-condensation domino reaction over Ce- and Bi-based CeBi mixed oxide mixtures
Varga, Gábor,Kukovecz, ákos,Kónya, Zoltán,Sipos, Pál,Pálinkó, István
, p. 308 - 315 (2019/11/29)
Both Bi- and Ce-based CeBi mixed oxides were prepared by a modified sol-gel process from their precursor salts. The mixed as well as the parent oxides were characterized by X-ray diffractometry, Raman, XPS, UV–DRS and X-ray photoelectron spectroscopies, ICP–OES method, scanning and transmission electron microscopies as well as BET surface area, CO2- and NH3-temperature-programmed desorption measurements. After characterizing the morphology, the acid-base properties, the oxidation states of the cationic components and the porosity of these structures, their catalytic activities were probed in the Koevenagel condensation of benzaldehyde and diethyl malonate and the toluene oxidation to benzaldehyde reactions. Based on the catalytic activities of the oxides in the individual reactions, a catalyst mixture from the Bi- and Ce-based mixed oxides was used successfully in the toluene to benzaldehyde oxidation and benzaldehyde to benzylidene malonate Knoevenagel condensation domino reaction under environmentally benign conditions.
New compounds having skin whitening activity and medical use thereof
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Paragraph 0070-0076, (2017/11/23)
The present invention relates to novel compounds having skin whitening activity and a medical use thereof, wherein the novel compounds are represented by chemical formula 1. The compounds according to the present invention have skin whitening activity tha
PROCESS FOR THE PREPARATION OF AN ARYL OXIME AND SALTS THEREOF
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Page/Page column 25; 26, (2013/05/09)
The invention relates to a process for the preparation of 3-cyano-3-{4-[(4-{[(2Z)-2-(methoxyimino)-2-phenylethyl] oxy} benzyl) oxy] phenyl} propanoic acid or salts thereof. In one form, the invention relates to the process for the preparation of (-)-3-cyano-3-{4-[(4-{[(2Z)-2-(methoxyimino)-2-phenylethyl]oxy}benzyl)oxy]phenyl}propanoic acid and conversion of the (-)-enantiomer to the sodium salt, sodium 3-cyano-3-{4-[(4-{[(2Z)-2-(methoxyimino)-2-phenylethyl]oxy}benzyl)oxy] phenyl}propanoate.
AGONISTS OF GPR40
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Page/Page column 77-78, (2012/02/05)
The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are there-fore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.
First bovine serum albumin-promoted synthesis of enones, cinnamic acids and coumarins in ionic liquid: An insight into the role of protein impurities in porcine pancreas lipase for olefinic bond formation
Sharma, Nandini,Sharma, Upendra K.,Kumar, Rajesh,Katoch, Nidhi,Kumar, Rakesh,Sinha, Arun K.
scheme or table, p. 871 - 878 (2011/06/19)
During studies on exploiting the catalytic promiscuity of crude porcine pancreas lipase (PPL) in ionic liquid for C=C bond formations, bovine serum albumin (BSA) was found to be competing for these reactions. After a detailed investigation, we establish that these transformations are possible by unspecific protein catalysis rather than catalytic promiscuity of "PPL" - a first insight into the role of protein impurities in crude enzyme. Thus, a novel and highly efficient, environmentally friendly approach involving synergistic catalysis by bovine serum albumin-1-butyl-3- methylimidazolium bromide (BSA-[bmim]Br) has been developed for the synthesis of (E)-α,β-unsaturated compounds including a one-pot cascade synthesis of cinnamic acids and coumarins via aldol, Knoevenagel and Knoevenagel-Doebner condensations.
Chromophore Coated Metal Oxide Particles
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, (2009/12/05)
The invention provides coated metal oxide particles, wherein metal oxide particles are coated with at least one type of crosslinkable chromophore with UV-A and/or UV-B and/or UV-C filter and/or broadband activity and optionally at least one type of crossl
Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: Virtual screening, synthesis, and biological evaluation
Deng, Guanghui,Li, Weihua,Shen, Jianhua,Jiang, Hualiang,Chen, Kaixian,Liu, Hong
body text, p. 5497 - 5502 (2009/05/30)
The identification of a novel pyrazolidine-3,5-dione based scaffold hit compound as Farnesoid X receptor (FXR) partial or full agonist has been accomplished by means of virtual screening techniques. A series of pyrazolidine-3,5-dione derivatives (1a-u and
NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
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Page/Page column 74, (2010/02/11)
The present invention relates to novel compounds accelerating the activity of Peroxisome proliferator-activated receptor gamma (PPARγ) and alpha (PPARα), processes of preparing the same, and pharmaceutical compositions containing the same as an active agent.
An Efficient Knoevenagel Condensation Catalyzed by LaCl3.7H 2O in Heterogeneous Medium
Narsaiah, A. Venkat,Nagaiah
, p. 3825 - 3832 (2007/10/03)
Knoevenagel condensation was carried out in absence of solvent with a mild Lewis acid Lanthanum(III) chloride, to prepare substituted alkenes. A systematic study of the reaction to establish the generality of the method has been undertaken with various aldehydes and active methylene compounds.
Barbituric acid derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and/or matrix metalloproteinases
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Page/Page column 42, (2008/06/13)
The present application describes novel barbituric acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, L, R1, R2, R3, R4, R5, n, W, U, X, Y, Z, U
