230617-82-0

Upstream product

• 2397-77-5 Ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate 
• 93-91-4 1-phenylbutan-1,3-dione 
• 76782-46-2 ethyl 6-phenyl-2,4,6-trioxohexanoate 

Downstream Products

• 2398-05-2 4-Oxo-6-phenyl-4H-pyran-2-carbaldehyde 
• 1449030-00-5 2-chloro-N-[(cyclohexylcarbamoyl)(4-oxo-6-phenyl-4Hpyran-2-yl)methyl]-N-p-tolylbenzamide 
• 1449030-01-6 N-[(tert-butylcarbamoyl)(4-oxo-6-phenyl-4H-pyran-2-yl)methyl]-N-p-tolylbenzamide 
• 1449030-02-7 2-chloro-N-[(cyclohexylcarbamoyl)(4-oxo-6-phenyl-4Hpyran-2-yl)methyl]-N-(4-methoxyphenyl)benzamide 
• 1449030-03-8 N-[(tert-butylcarbamoyl)(4-oxo-6-phenyl-4H-pyran-2-yl)methyl]-2-chloro-N-(4-methoxyphenyl)benzamide 
• 1415396-57-4 C₂₃H₂₃N₂O₂⁽¹⁺⁾*I^(1-) 
• 1415396-55-2 C₂₁H₁₉N₂O₂⁽¹⁺⁾*I^(1-) 
• 1415396-53-0 1-methyl-3-[(4-oxo-6-phenyl-4H-pyran-2-yl)methyl]-benzimidazolium iodide 
• 1415396-48-3 C₁₆H₁₅N₂O₂⁽¹⁺⁾*Br^(1-) 

Relevant academic research and scientific papers

Synthesis, spectroscopic and DFT studies of novel fluorescent dyes: 3-Aminoimidazo[1,2-a]pyridines possessing 4-pyrone moieties

A series of novel imidazo[1,2-a]pyridines possessing 4-pyrone ring were synthesized by three-component condensation of 4-pyrone carbaldehydes, 2-aminopyridines and isocyanides. Bismuth (III) chloride was used as a catalyst in these reactions and desired products were synthesized in good yields at a very short period of time under solvent free conditions. UV-Vis absorption and fluorescence emission spectra of these compounds were investigated. It shown that two of these compounds (10f and 10g) exhibit intense fluorescence in dichloromethane. Optimized ground-state molecular geometries and orbital distributions of these two fluorescent dyes were obtained using density functional theory (DFT). Thermogravimetric analysis and electrochemical properties of these compounds were also studied.

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction

Fourteen novel bis-carboxamide derivatives of 4-pyrones were designed and synthesized via Ugi four-component reactions of 4-pyrone carbaldehydes, aromatic amines, isocyanides and carboxylic acids. The cytotoxic activity of synthesized derivatives was eval

Substituent effects on the 4π + 2π cycloadditions of 4H-pyran-4-one derivatives

The simple y-pyranones 4,5, and 6 undergo 4π + 2π cycloaddition reactions with Danishefsky's diene 8 and azomethine ylides 12,16, and 25 to give a range of cycloadducts. The position of the electron-withdrawing group is the decisive factor in these reactions, with the 2-substituted derivatives 5 and 6 being less reactive than the 3-substituted γ-pyranone 4. The esters, 4 and 5, react via addition across the 2,3-C=C bond of the pyranone ring, whilst the aldehyde 6 reacts via addition across the C=O of the carbaldehyde group.