23063-36-7

Basic information

• Product Name: 1-(DICHLOROMETHYL)-4-METHYLBENZENE
• Synonyms: 4-Methyl-1-(dichloromethyl)benzene;Benzene, 1-(dichloromethyl)-4-methyl-;p-Methylbenzal chloride;1-(DICHLOROMETHYL)-4-METHYLBENZENE;1-Methyl-4-(dichloromethyl)benzene;4-Methylphenyldichloromethane
• CAS NO: 23063-36-7
• Molecular Formula: C₈H₈Cl₂
• Molecular Weight: 175.06
• Mol File: 23063-36-7.mol
• Article Data: 14

Chemical Properties

• Melting Point: 48.5°C
• Boiling Point: 228.7°C (estimate)
• Appearance: /
• Density: 1.2520 (estimate)
• Refractive Index: 1.5544 (estimate)
• CAS DataBase Reference: 1-(DICHLOROMETHYL)-4-METHYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(DICHLOROMETHYL)-4-METHYLBENZENE(23063-36-7)
• EPA Substance Registry System: 1-(DICHLOROMETHYL)-4-METHYLBENZENE(23063-36-7)

Safety Data

• Hazardous Substances Data: 23063-36-7(Hazardous Substances Data)

Usage

General Description

1-(Dichloromethyl)-4-methylbenzene, also known as p-Xylene alpha,alpha-dichloride, is a chemical compound with the chemical formula C8H8Cl2. It is characterized by its aromaticity, comprising a xylene group, a type of methylbenzene with two methyl groups attached to the benzene ring. In this particular compound, it also has two chlorides attached to one of the attached methyl groups. Like many similar aromatic compounds, it is often used in industrial applications, particularly in the chemical or manufacturing industries. Information about its physical properties, toxicological data, and other characteristics may vary, and proper handling and usage instructions should always be followed to ensure safety.

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 12190-75-9 chloroamine 
• 7664-93-9 sulfuric acid 
• 104-82-5 4-Methylbenzyl chloride 
• 18484-04-3 2-((4-methylbenzyl)oxy)tetrahydro-2H-pyran 
• 89200-92-0 trimethyl(4-methylbenzyloxy)silane 
• 106-42-3 para-xylene 
• 4893-33-8 tris(pentafluoro phenyl) methanol 
• 7782-50-5 chlorine 
• 56-23-5 tetrachloromethane 
• 108-88-3 toluene 

Downstream Products

• 65915-30-2 bis-4-(methylbenzyl)-diselenide 
• 160594-72-9 N,N-diethyl-4-methylselenobenzamide 
• 91763-35-8 1-(p-methylphenyl)-1-pentanol 
• 96394-99-9 9-(p-tolyl)methylenecyclooctatrienyl lithium 
• 92317-55-0 1-Chlor-1-(4-tolyl)-2,2,3,3-tetramethyl-cyclopropan 
• 92582-75-7 1-Chlor-1-<4-tolyl>-2--cyclopropan 
• 104-87-0 4-methyl-benzaldehyde 
• 22440-35-3 trans-2-(4-methylbenzenyl)-3-phenyl-oxirane 
• 100-21-0 terephthalic acid 
• 106-42-3 para-xylene 

Relevant articles and documents

One-pot, oxidative and selective conversion of benzylic silyl and tetrahydropyranyl ethers to gem-dichlorides using trichloroisocyanuric acid and triphenylphosphine as an efficient and neutral system

A one-pot and oxidative method is described for the first time for the conversion of benzylic trimethylsilyl (TMS) and tetrahydropyranyl (THP) ethers to gem-dichlorides using trichloroisocyanuric acid (TCCA) and triphenylphosphine (PPh3) in neutral media. Various theses substrates containing electron withdrawing or donating groups can be efficiently converted to their corresponding gem-dichlorides in good to excellent yields. The present method shows a high degree of chemoselectivity, and due to its one-pot nature is in accordance with green chemistry.

Halogenation through Deoxygenation of Alcohols and Aldehydes

An efficient reagent system, Ph3P/XCH2CH2X (X = Cl, Br, or I), was very effective for the deoxygenative halogenation (including fluorination) of alcohols (including tertiary alcohols) and aldehydes. The easily available 1,2-dihaloethanes were used as key reagents and halogen sources. The use of (EtO)3P instead of Ph3P could also realize deoxy-halogenation, allowing for a convenient purification process, as the byproduct (EtO)3Pa?O could be removed by aqueous washing. The mild reaction conditions, wide substrate scope, and wide availability of 1,2-dihaloethanes make this protocol attractive for the synthesis of halogenated compounds.

Rasta resin-triphenylphosphine oxides and their use as recyclable heterogeneous reagent precursors in halogenation reactions

Heterogeneous polymer-supported triphenylphosphine oxides based on the rasta resin architecture have been synthesized, and applied as reagent precursors in a wide range of halogenation reactions. The rasta resin-triphenylphosphine oxides were reacted with either oxalyl chloride or oxalyl bromide to form the corresponding halophosphonium salts, and these in turn were reacted with alcohols, aldehydes, aziridines and epoxides to form halogenated products in high yields after simple purification. The polymersupported triphenylphosphine oxides formed as a byproduct during these reactions could be recovered and reused numerous times with no appreciable decrease in reactivity.