230964-57-5Relevant articles and documents
Synthesis and antibacterial activity of 1β-methylcarbapenem having a 1,3-diazabicyclo[3.3.0]octan-4-one moiety, Part II
Oh, Chang-Hyun,Lee, Seung Chan,Park, Sung-Jin,Lee, In-Kyu,Nam, Ki Hong,Lee, Ki-Soo,Chung, Bong-Young,Cho, Jung-Hyuck
, p. 111 - 114 (2007/10/03)
The synthesis of a new series of 1β-methylcarbapenems having a 1,3- diazabicyclo[3.3.0]octan-4-one moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria are tested and the effect of substituent on the bicyclic ring was investigated. A particular compound (11h) having aminoethyl group showed the most potent antibacterial activity.