23112-27-8

Upstream product

• 1118-66-7 4-Aminopent-3-en-2-one 
• 98-88-4 benzoyl chloride 
• 123-54-6 acetylacetone 
• 65-85-0 benzoic acid 
• 55-21-0 benzamide 

Downstream Products

• 79309-91-4 4-benzoylaminopent-3-en-2-thione 
• 3274-53-1 3,5-dimethyl-2-phenyl-1H-pyrrole 
• 936482-29-0 N-((Z)-1,3-dimethylbuta-1,3-dienyl)benzamide 
• 1629603-14-0 C₂₁H₁₉NO 
• 1629603-18-4 C₂₁H₁₇NO 
• 1629603-22-0 C₂₃H₃₁NSi 
• 1629603-31-1 C₁₄H₁₁N 
• 1033438-00-4 2-methyl-6-phenyl-pyridin-4-yl nonaflate 
• 4620-51-3 1-(4-methyl-2-phenyloxazol-5-yl)ethanone 
• 33883-97-5 2-methyl-6-phenyl-pyridin-4-ol 
• 24374-32-1 exo-N-bicyclo[2.2.1]heptan-2-yl-benzamide 
• 936482-38-1 3-benzylamino-3,5-dimethylcyclohexa-1,4-dienecarboxylic acid methyl ester 

Relevant academic research and scientific papers

A rapid access to substituted oxazoles via PIFA-mediated oxidative cyclization of enamides

A facile and rapid access to multi-substituted oxazoles has been achieved under mild reaction conditions in a short reaction time. Reaction of enamides 1 with [bis(trifluoroacetoxy)iodo]benzene (PIFA) in trifluoroethanol (TFE) at room temperature for 15?min afforded the desired oxazoles 2 in moderate to excellent yields (58–98%). A wide range of functional group tolerance has been observed for these transformations.

New 4-pyridyl nonaflates as precursors for push-pull solvatochromic dyes

2,6-Disubstituted 4-pyridyl nonaflates including methyl, phenyl, 2-thienyl and 2-furyl groups were prepared by cyclocondensation reactions of the appropriate β-ketoenamides. Palladium-catalyzed cross-couplings (Suzuki-Miyaura, Mizoroki-Heck and Sonogashira reactions) led to buildings blocks that are direct precursors for the envisioned synthesis of push-pull solvatochromic dyes. Georg Thieme Verlag Stuttgart? New York.

A new and flexible synthesis of 4-hydroxypyridines: Rapid access to caerulomycins A, e and functionalized terpyridines

A simple new protocol for the preparation of substituted 4-hydroxypyridines form inexpensive commercially available reagents was reported. The synthetic sequence involved three stages with an intramolecular aldol-type condensation of readily available ena

SUBSTITUTED 4-HYDROXYPYRIDINES

The present invention relates to substituted 4-hydroxypyridines as well as their derivatives, a process for producing substituted 4-hydroxypyridines and their derivatives as well as the use of these compounds.

Radical transfer hydroamination with aminated cyclohexadienes using polarity reversal catalysis: Scope and limitations

The synthesis of various new 1-aminated-2,5-cyclohexadienes is described. These reagents can be used in radical transfer hydroaminations of unactivated and electron-rich double bonds. With thiols as polarity reversal catalysts good yields are obtained. The radical hydroamination occurs with good to excellent anti-Markovnikov selectivity. Many functional groups such as alcohols, silyl ethers, phosphonates, arylbromides, imides, amides, and also acidic protons are tolerated under the reaction conditions. DFT calculations provide insights into the aromatization of silyl, alkyl, and aminyl substituted cyclohexadienyl radicals to generate the corresponding C-, Si-, and N-centered radicals.

ENAMINE CHEMISTRY-XXII; THE PREPARATION OF 4-ACYLAMINOPENT-3-EN-2-ONES AND THE CORRESPONDING ENAMINO-THIONES

Acylation of 4-aminopent-3-en-2-one, 5, with different acid chlorides, RCOCl (R=Me, Me2CH, Me3C, C6H5, ClCH2) gives only N-acylated products, 6, in high yields.The N-acylated enaminones, 5, are shown only to exist in the Z-s-Z form in solution.The UV spec