2317-30-8Relevant articles and documents
A Palladium-Catalyzed Domino Procedure for the Synthesis of Unsymmetrical Ureas
Chen, Bo,Peng, Jin-Bao,Ying, Jun,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 2820 - 2824 (2018/08/17)
A palladium-catalyzed carbonylative procedure for the synthesis of unsymmetrical ureas has been developed. This one-pot one-step cascade procedure is consisted by three individual processes: carbonylation, Curtius rearrangement, and nucleophilic addition. A series of unsymmetrical ureas were prepared from easily available aryl iodides and amines in moderate to excellent yields. This procedure provides a convenient and practical approach for unsymmetrical urea synthesis. (Figure presented.).