23269-09-2Relevant academic research and scientific papers
Synthesis and electrochemical evaluation of 2-substituted imidazolium salts
Hogan, David T.,Sutherland, Todd C.
supporting information, (2018/03/22)
Herein, we report the synthesis, electrochemical, and computational evaluation of six 2-substituted imidazolium bromides and six 2-substituted imidazolium triflates. All final compounds were obtained in 2 or fewer synthetic steps from inexpensive starting
Lithiation of 1-Benzylimidazole. A Hypothesis on the Regioselectivity of the Electrophilic Attacks on the Lithiated Species
Moreno-Manas, M.,Bassa, J.,Llado, N.,Pleixats, R.
, p. 673 - 678 (2007/10/02)
Sequential lithiations of 1-benzylimidazole, 1, and of 1-benzyl-1,2,4-triazole,2, followed by treatment with electrophiles others than alkyl halides result in reactions at C-2.However, benzyl halides and, to a certain extent, iodomethane react at the N-benzyl carbon atom.An explanatory hypothesis based on steric ortho effects is advanced.
Reaction of Dimethyl N-Aryl- and N-Alkylcarbonimidodithioates with Aminoacetaldehyde Diethyl Acetal: A Direct Synthesis of 1-Aryl- and 1-Alkyl-2-methylthioimidazoles
Pooranchand, Dinah,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 1136 - 1138 (2007/10/02)
The reaction of dimethyl N-aryl- or N-alkylcarbonimidodithioates with aminoacetaldehyde diethyl acetal in refluxing acetic acid affords 1-aryl or 1-alkyl-2-methylthioimidazoles in good yields.Dimethyl N-isopropylcarbonimidodithioate gave 1-isopropylimidazole-2(3H)-thione under similar conditions.
