23340-25-2

Basic information

• Product Name: Butanenitrile, 3-oxo-2-(phenylmethylene)-
• CAS NO: 23340-25-2
• Molecular Formula: C11H9NO
• Molecular Weight: 171.199
• Mol File: 23340-25-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Butanenitrile, 3-oxo-2-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanenitrile, 3-oxo-2-(phenylmethylene)-(23340-25-2)
• EPA Substance Registry System: Butanenitrile, 3-oxo-2-(phenylmethylene)-(23340-25-2)

Safety Data

• Hazardous Substances Data: 23340-25-2(Hazardous Substances Data)

Upstream product

• 2469-99-0 Cyanoaceton 
• 100-52-7 benzaldehyde 
• 6497-21-8 1-(5-methyl-1,2-oxazol-4-yl)ethanone 
• 75-05-8 acetonitrile 
• 3405-77-4 5-methylisoxazole 3-carboxylic acid 

Downstream Products

• 1404447-00-2 3-benzyl-5-(1H-indol-6-yl)-2-methylpyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1404446-99-6 3-benzyl-2-methyl-5-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1404446-94-1 3-benzyl-5-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1404446-88-3 3-benzyl-2-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1404449-35-9 4-benzyl-3-methyl-1H-pyrazol-5-amine 
• 84831-51-6 2-acetyl-3-phenylpropanenitrile 
• 132577-38-9 4-benzal-3-methyl-1-phenylisothiocyanatopyrazol-5-one 

Relevant articles and documents

The Convenient Synthesis of 11-Methyl-3,8-disubstituted-12-aryl-3,4,7,8,9,12-hexahydro-1H-chromeno[2,3-b]quinoline-1,10(2H)-dione Derivatives

The 2-arylidene-3-oxobutanenitrile derivatives 2 were prepared by the Knoevenagel condensation between aldehydes and 3-oxobutanenitrile 1, which was obtained by acid hydrolysis of β-aminocrotononitrile. 3-Acetyl-2-amino-4H-chromen-5(6H)-one derivatives 3 were synthesized by reaction of 2-arylidene-3-oxobutanenitrile 2 and 5-substituted-1,3-cyclohexanedione in ethylene glycol. The 11-methyl-3,8-disubstituted-12-aryl-3,4,7,8,9,12-hexahydro-1H-chromeno[2,3-b]quinoline-1,10(2H)-dione derivatives 4 were obtained by Friedl?nder reaction of compounds 3 with 5-substituted-1,3-cyclohexanedione, using p-toluenesulfonic acid monohydrate as catalyst. The structures of all novel compounds were characterized by elemental analysis, IR, MS, and 1H NMR spectra. The crystal and molecular structure of compound 4f has been determined by single crystal XRD analysis.

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

ON THE RING CLEAVAGE OF ISOXAZOLES: A NOTE

A new heterocyclic compound is obtained from the basic cleavage of an isoxazole ring in the presence of an aldehyde.