233598-99-7

Upstream product

• 462-06-6 fluorobenzene 
• 485-47-2 indan-1,2,3-trione hydrate 
• 208588-17-4 2,2-Bis-(4-fluoro-phenyl)-indan-1,3-dione 

Downstream Products

• 1437803-06-9 3-[bis-(4’-fluorophenyl)methyl]-3-hydroxy-2-phenylamino-2,3-dihydroisoindol-1-one 
• 1437802-98-6 4-[bis-(4’-fluorophenyl)methyl]-benzo[d][1,2]oxazin-1-one 
• 71824-24-3 2-(2-aminoethyl)-1H-isoindole-1,3(2H)-dione 
• 457-68-1 4,4'-difluorodiphenylmethane 

Relevant academic research and scientific papers

Facile synthesis of 3-(diarylmethylene)isobenzofuranones, 4-(diarylmethyl)-1(2H)-phthalazinones and diarylmethanes

Reflux of 2,2-diaryl-1,3-indanediones in ethyleneglycol with a catalytic amount of triethylamine affords 3-(diarylmethylene)isobenzofuranones in very good yields. The latter produces 4-diarymethyl-1(2H)-phthalazinones under reflux in hydrazine hydrate (99%), and diarylmethanes upon stirring in ethylenediamine.

Acid-Catalyzed Condensations of Ninhydrin with Aromatic Compounds. Preparation of 2,2-Diaryl-1,3-indanediones and 3-(Diarylmethylene)isobenzofuranones 1

Ninhydrin (1) reacts with aromatic compounds in acid solution to give condensation products. In H2SO4, 1 reacts with arenes to give 2,2-diaryl-1,3-indanediones (2a-f). In superacidic triflic acid (CF3SO3H, TfOH)