233684-03-2

Basic information

• Product Name: N,N-diethyl-N'-(o-carboxyphenyl)urea
• Synonyms: N,N-diethyl-N'-(o-carboxyphenyl)urea
• CAS NO: 233684-03-2
• Molecular Weight: 236.271
• Mol File: 233684-03-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N-diethyl-N'-(o-carboxyphenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-N'-(o-carboxyphenyl)urea(233684-03-2)
• EPA Substance Registry System: N,N-diethyl-N'-(o-carboxyphenyl)urea(233684-03-2)

Safety Data

• Hazardous Substances Data: 233684-03-2(Hazardous Substances Data)

Upstream product

• 14128-51-9 2-(diethylamino)-4H-benzo[d][1,3]oxazin-4-one 
• 118-92-3 anthranilic acid 
• 109-89-7 diethylamine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 88-10-8 N,N-diethylcarbamyl chloride 
• 233684-00-9 4-[2-(3,3-diethylureido)benzoyl]morpholine 
• 78554-91-3 2-(3,3-diethylureido)-N,N-diethylbenzamide 

Downstream Products

• 118-48-9 isatoic anhydride 

Relevant articles and documents

Antidepressant activity of carbamates and urea derivatives

Thirteen (13) compounds of N-phenyl-O-alkyl carbamates (1 and 3), N,N-diethyl-N′-alkyl/aryl/phenylpiperazinoureas (4-6, 8-12), N-phenyl-N′-phenylpiperazino/imidazoureas (2, 7), and N-ethyl-(N′- phenylpiperazino) thioureas 13 were synthesized and tested for their antidepressant-like activity in mice. It was found that compound N-phenyl-O-heptyl carbamate 1 and N-phenyl-N′-phenylpiperazinourea 2 showed 32.5 and 27.7% antidepressant activity in the forced swim test in mice, respectively. Considering other carbamates it was found that a decrease in alkyl chain length caused a marked decline in the antidepressant activity. Compounds 1-4 show even higher activities in the forced swim test than the standard phenelzine. Springer Science+Business Media, LLC 2011.

Aromatic 2-(thio)ureidocarboxylic acids as a new family of modulators of multidrug resistance-associated protein 1: Synthesis, biological evaluation, and structure - Activity relationships

Four series of aromatic carboxylic acids were prepared with a urea or thiourea moiety at the neighboring position to the carboxyl group and benzene or thiophene as aromatic scaffold. Using a calcein AM assay, these compounds were evaluated as inhibitors o