233689-90-2

Upstream product

• 105562-75-2 N²-(tert-butyloxycarbonyl)-N⁵-(benzyloxycarbonyl)-2(S),5-diaminopentanol 
• 507-09-5 tiolacetic acid 
• 233689-91-3 (S)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentylmethanesulfonate 
• 2480-93-5 Boc-Orn(Z)-OH 

Downstream Products

• 252940-43-5 Boc-NH-CH((CH₂)3NHZ)-CH₂-S-(CH₂)3COOtBu 
• 252940-46-8 4-((S)-2-Amino-5-benzyloxycarbonylamino-pentylsulfanyl)-butyric acid 
• 274901-50-7 Boc-D-Phe-Pro-Arg(Cbz2)-ψ[CH2SO2NH]-Gly-OEt 
• 274901-51-8 C₄₁H₅₃N₇O₁₀S 
• 274901-48-3 Boc-Pro-Arg-(Cbz2)-ψ[CH2SO2NH]-Gly-OEt 
• 274901-49-4 C₃₂H₄₄N₆O₉S 
• 274901-46-1 Boc-Arg(Cbz2)-ψ[CH2SO2NH]-Gly-OEt 
• 1054691-10-9 Arg-(Cbz2)-ψ[CH2SO2NH]-Gly-OEt 
• 274901-47-2 C₂₇H₃₇N₅O₈S 
• 1053650-83-1 C₂₂H₂₉N₅O₆S 
• 274901-43-8 Boc-Orn(Cbz)-ψ[CH2SO2NH]-Gly-OEt 
• 274901-42-7 (5-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-pentane-1-sulfinylamino)-acetic acid ethyl ester 
• 274901-45-0 (4-tert-butoxycarbonylamino-5-sulfamoyl-pentyl)-carbamic acid benzyl ester 
• 274901-44-9 (4-tert-butoxycarbonylamino-5-sulfinamoyl-pentyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of α- and β-substituted aminoethane sulfonamide arginine- glycine mimics

In this paper we present a synthesis of both α- and β-substituted aminoethane sulfonamide arginine mimics. The α-substituted sulfonamides were obtained starting from an alkene, whereas the β-substituted sulfonamides were derived from an amino acid derivative.

The synthesis of a new class of oxytocin antagonists

The synthesis of a new class of oxytocin antagonists, with significantly modified C-terminal part, is described. The chemistry of the Mitsunobu reaction was applied to obtain the key derivatives. In spite of the extensive modifications of previously described compound F792, the peptides retain biological activity as oxytocin antagonists.