23450-31-9

Basic information

• Product Name: 4-BENZYLBENZONITRILE
• Synonyms: 4-BENZYLBENZONITRILE
• CAS NO: 23450-31-9
• Molecular Formula: C₁₄H₁₁N
• Molecular Weight: 193.24
• Product Categories: pharmacetical
• Mol File: 23450-31-9.mol
• Article Data: 77

Chemical Properties

• Boiling Point: 334.9°Cat760mmHg
• Flash Point: 157°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.000124mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 4-BENZYLBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLBENZONITRILE(23450-31-9)
• EPA Substance Registry System: 4-BENZYLBENZONITRILE(23450-31-9)

Safety Data

• Hazardous Substances Data: 23450-31-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H11N/c15-11-14-8-6-13(7-9-14)10-12-4-2-1-3-5-12/h1-9H,10H2

Upstream product

• 623-26-7 terephthalonitrile 
• 67-56-1 methanol 
• 101-49-5 2-(benzyl)-1,3-dioxolane 
• 623-00-7 4-bromobenzenecarbonitrile 
• 73085-90-2 benzyltitanium triisopropoxide 
• 1503-49-7 p-cyanobenzophenone 
• 16635-23-7 phenyltriisopropoxytitanium(IV) 
• 17201-43-3 4-cyanobenzyl bromide 
• 13391-47-4 4-cyanobenzhydrol 
• 100-44-7 benzyl chloride 
• 623-03-0 4-Cyanochlorobenzene 
• 114-70-5 sodium phenylacetate 
• 85-01-8 phenanthrene 
• 2945-41-7 triethylgermylmethylbenzene 

Downstream Products

• 1313757-14-0 C₂₁H₁₆N₂O 
• 1313757-11-7 1-(bis(4-iodophenyl)methyl)-1H-1,2,4-triazole 
• 1503-49-7 p-cyanobenzophenone 
• 100866-27-1 4-benzyl-benzaldehyde seqtrans-oxime 
• 67468-65-9 4-benzylbenzaldehyde 
• 620-86-0 4-Benzylbenzoic acid 

Relevant articles and documents

Photoalkylation of Dicyanoarenes with Alkyltriphenylborate Salts

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Nickel-Catalyzed Reductive Cross-Coupling of Benzylic Sulfonium Salts with Aryl Iodides

A nickel-catalyzed cross-electrophile coupling of benzylic sulfonium salts with aryl iodides has been developed, providing direct access to diarylalkanes from readily available and stable coupling partners. Preliminary mechanistic studies suggest that the C-S bond cleavage proceeds through a single-electron transfer process to generate a benzylic radical.

Desulfurative Ni-Catalyzed Reductive Cross-Coupling of Benzyl Mercaptans/Mercaptoacetates with Aryl Halides

The C-S activation and sulfur removal from native thiols is challenging, which limits their application as feedstock materials in organic synthesis despite their natural abundance. Herein, we introduce a per-/polyfluoroaryl moiety, which serves as a redox-active scaffold, into sp3-hybridized thiols to activate the C-S bond. Using a Ni catalyst with MgBr2 as an additive, the S group can be removed to yield an aliphatic radical that can react with an aryl halide in a reductive cross-coupling.