2349-71-5

Usage

Uses

Used in the Food Industry:
2-Isopropylhydroquinone is used as an antioxidant and stabilizer for [application reason] preventing the formation of free radicals and inhibiting the oxidation of fats and oils in food products. This helps to extend the shelf life and maintain the quality of these products.
Used in Antioxidant Formulations:
In the context of food preservation, 2-isopropylhydroquinone is used as an ingredient in antioxidant formulations for [application reason] its ability to prevent the oxidation of food components, thus protecting them from spoilage and rancidity.
Used in FDA-Approved Food Products:
2-Isopropylhydroquinone is used as a preservative in certain food products for [application reason] its safety and efficacy in maintaining the quality and extending the shelf life of these products, as approved by the FDA.

InChI:InChI=1/C9H12O2/c1-6(2)8-5-7(10)3-4-9(8)11/h3-6,10-11H,1-2H3

Upstream product

• 108-20-3 di-isopropyl ether 
• 123-31-9 hydroquinone 
• 67-63-0 isopropyl alcohol 
• 7664-39-3 hydrogen fluoride 
• 618-45-1 3-isopropylhydroxybenzene 
• 15232-10-7 2-isopropyl-1,4-benzoquinone 

Downstream Products

• 92474-89-0 2-Isopropyl-5-sulfo-hydrochinon 
• 2349-79-3 2-Isopropyl-5-(1,1,3,3-tetramethyl-butyl)-hydrochinon 
• 2349-78-2 5-tert-butyl-2-isopropylhydroquinone 
• 13522-86-6 2-iso-propyl-4-methoxyphenol 
• 4132-71-2 2-Isopropyl-1,4-dimethoxybenzene 

Relevant academic research and scientific papers

Iron-catalyzed arene C-H hydroxylation

The sustainable, undirected, and selective catalytic hydroxylation of arenes remains an ongoing research challenge because of the relative inertness of aryl carbon-hydrogen bonds, the higher reactivity of the phenolic products leading to over-oxidized by-products, and the frequently insufficient regioselectivity. We report that iron coordinated by a bioinspired L-cystine-derived ligand can catalyze undirected arene carbon-hydrogen hydroxylation with hydrogen peroxide as the terminal oxidant. The reaction is distinguished by its broad substrate scope, excellent selectivity, and good yields, and it showcases compatibility with oxidation-sensitive functional groups, such as alcohols, polyphenols, aldehydes, and even a boronic acid. This method is well suited for the synthesis of polyphenols through multiple carbon-hydrogen hydroxylations, as well as the late-stage functionalization of natural products and drug molecules.

Candida antarctica lipase B-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxy groups

Candida antarctica lipase B proved to be highly active in the deacylation of substituted hydroquinones and resorcinols acylated at both phenolic hydroxy groups. The deacylation reactions were much faster than the corresponding direct acylations of these dihydroxybenzenes catalyzed by the same lipase. More importantly, they took place generally in a markedly regioselective manner: the acyloxy group remote from the substituent was preferentially cleaved. The main or exclusive products obtained were the regioisomers of those produced through the direct acylation of the dihydroxybenzenes. In the case of alkyl-substituted hydroquinone derivatives, the regioselectivity increased with an increase in the bulk of the substituent. In the case of 4-substituted diacylated resorcinols, the 3-O-monoacyl derivatives were obtained generally as the sole products. Quite interestingly, some secondary alcohols proved to act as better acyl acceptors than the corresponding primary alcohols in these enzymatic deacylations.

Secondary alcohols act as better nucleophiles than primary alcohols in the lipase-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyls

Candida antarctica lipase B (CAL-B) was found to be highly regioselective as well as active in the deacylation of resorcinols and hydroquinones acylated at both phenolic hydroxyls. Contrary to expectation, secondary alcohols acted as better nucleophiles than primary alcohols in these enzymatic deacylations.