23600-48-8

Basic information

• Product Name: Benzamide, N-(4-hydroxyphenyl)-4-methoxy-
• CAS NO: 23600-48-8
• Molecular Formula: C14H13NO3
• Molecular Weight: 243.262
• Mol File: 23600-48-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(4-hydroxyphenyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(4-hydroxyphenyl)-4-methoxy-(23600-48-8)
• EPA Substance Registry System: Benzamide, N-(4-hydroxyphenyl)-4-methoxy-(23600-48-8)

Safety Data

• Hazardous Substances Data: 23600-48-8(Hazardous Substances Data)

Upstream product

• 123-30-8 4-amino-phenol 
• 100-07-2 4-methoxy-benzoyl chloride 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 98-95-3 nitrobenzene 
• 100-65-2 N-Phenylhydroxylamine 
• 13664-49-8 N-phenyl-p-methoxybenzohydroxamic acid 
• 7465-88-5 4-methoxy-N-phenylbenzamide 
• 155164-68-4 4,5-Dichloro-2-(4-methoxy-benzoyl)-2H-pyridazin-3-one 

Downstream Products

• 321691-41-2 C₁₄H₁₁NO₃ 
• 321691-03-6 4-amino-N-(4-methylbenzoyl)-2-chlorophenol 
• 321947-10-8 4-amino-N-(4-methoxybenzoyl)-2-chlorophenol 
• 90446-42-7 N-(4-Hydroxy-3,5-bis-pyrrolidin-1-ylmethyl-phenyl)-4-methoxy-benzamide 

Relevant articles and documents

Redox-Neutral Selenium-Catalysed Isomerisation of para-Hydroxamic Acids into para-Aminophenols

A selenium-catalysed para-hydroxylation of N-aryl-hydroxamic acids is reported. Mechanistically, the reaction comprises an N?O bond cleavage and consecutive selenium-induced [2,3]-rearrangement to deliver para-hydroxyaniline derivatives. The mechanism is studied through both 18O-crossover experiments as well as quantum chemical calculations. This redox-neutral transformation provides an unconventional synthetic approach to para-aminophenols.

Novel 3/4-((Substitutedbenzamidophenoxy)methyl)-N-hydroxybenzamides/propenamides and its use

The present invention relates to novel 3/4-((substituted benzamidophenoxy) methyl) -N-hydroxy benzamide/propenamide, as a histone deacetylase (HDAC) inhibitor, and to an anticancer composition comprising the same as an active ingredient. More specifically

Introduction of a hydroxy group at the para position and N-iodophenylation of N-arylamides using phenyliodine(III) bis(trifluoroacetate)

The reaction of anilides with phenyliodine(III) bis(trifluoroacetate) (PIFA) in trifluoroacetic acid (TFA), TFA-CHCl3, or hexafluoroisopropyl alcohol (HFIP) is described. When the acyl group of the anilide is highly electronegative, such as trifluoroacetyl, or the phenyl group is substituted with an electron-withdrawing group, the 4-iodophenyl group is transferred from PIFA to the amide nitrogen to afford acetyldiarylamines. On the other hand, when the acyl group contains an electron-donating function, such as 4-methoxyphenyl, or the phenyl group is substituted with an electron-donating group, a trifluoroacetoxy group is transferred to the para position of the anilide aromatic ring. This group is hydrolyzed during workup to produce the corresponding phenol.