236418-15-8

Basic information

• Product Name: Cyclopropanecarboxylic acid, 1-[3-[(4-cyanophenyl)methyl]-1,2-dihydro-1-methyl-2-oxo-6-quinoxalinyl]-
• CAS NO: 236418-15-8
• Molecular Formula: C21H17N3O3
• Molecular Weight: 359.384
• Mol File: 236418-15-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 1-[3-[(4-cyanophenyl)methyl]-1,2-dihydro-1-methyl-2-oxo-6-quinoxalinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 1-[3-[(4-cyanophenyl)methyl]-1,2-dihydro-1-methyl-2-oxo-6-quinoxalinyl]-(236418-15-8)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 1-[3-[(4-cyanophenyl)methyl]-1,2-dihydro-1-methyl-2-oxo-6-quinoxalinyl]-(236418-15-8)

Safety Data

• Hazardous Substances Data: 236418-15-8(Hazardous Substances Data)

Upstream product

• 654055-09-1 3-(4-cyano-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid 
• 236418-12-5 1-(4-methylamino-3-nitro-phenyl)-1-cyclopropanecarboxylic acid 
• 236418-11-4 1-(4-chloro-3-nitro-phenyl)-1-cyclopropanecarboxylic acid 
• 72934-37-3 3-(4-chlorophenyl)-1-cyclopropanecarboxylic acid 
• 18910-26-4 2-amino-3-(4-cyano-phenyl)-propionic acid 
• 43229-87-4 3-(4-cyano-phenyl)-2-oxo-propionic acid 
• 236418-13-6 1-(3-amino-4-methylamino-phenyl)-cyclopropanecarboxylic acid 

Downstream Products

• 592465-38-8 4-{4-methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cyclopropyl]-3,4-dihydro-quinoxalin-2-ylmethyl}-benzonitrile 
• 246542-32-5 4-{[6-(1-(N-tert-butyloxycarbonylamino)-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)-methyl]-benzonitrile 
• 777044-08-3 N-{1-[3-(4-carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester 
• 246542-35-8 N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester 
• 246542-34-7 4-{[6-(1-cyclopentylamino-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl]-methyl}-benzonitrile 
• 246542-33-6 4-{[6-(1-amino-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)-methyl]-benzonitrile 

Relevant articles and documents

Heterocyclic thrombin inhibitors. Part 2: Quinoxalinone derivatives as novel, potent antithrombotic agents

Quinoxalinone derivatives as prototypes of dual thrombin and factor Xa inhibitors have been discovered. Nanomolar inhibition of both coagulation enzymes resulted in very potent antithrombotic activity in vitro.