777044-08-3Relevant articles and documents
Heterocyclic thrombin inhibitors. Part 2: Quinoxalinone derivatives as novel, potent antithrombotic agents
Ries, Uwe J.,Priepke, Henning W. M.,Hauel, Norbert H.,Handschuh, Sandra,Mihm, Gerhard,Stassen, Jean M.,Wienen, Wolfgang,Nar, Herbert
, p. 2297 - 2302 (2007/10/03)
Quinoxalinone derivatives as prototypes of dual thrombin and factor Xa inhibitors have been discovered. Nanomolar inhibition of both coagulation enzymes resulted in very potent antithrombotic activity in vitro.