246542-35-8

Basic information

• Product Name: N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester
• Synonyms: N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester
• CAS NO: 246542-35-8
• Molecular Weight: 512.608
• Mol File: 246542-35-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester(246542-35-8)
• EPA Substance Registry System: N-{1-[3-(4-cyano-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester(246542-35-8)

Safety Data

• Hazardous Substances Data: 246542-35-8(Hazardous Substances Data)

Upstream product

• 36239-09-5 ethyl chlorocarbonylacetate 
• 246542-34-7 4-{[6-(1-cyclopentylamino-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl]-methyl}-benzonitrile 
• 246542-32-5 4-{[6-(1-(N-tert-butyloxycarbonylamino)-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)-methyl]-benzonitrile 
• 236418-15-8 4-[(6-(1-carboxy-cyclopropan-1-yl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)-methyl]-benzonitrile 
• 246542-33-6 4-{[6-(1-amino-cyclopropyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)-methyl]-benzonitrile 
• 654055-09-1 3-(4-cyano-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid 
• 236418-12-5 1-(4-methylamino-3-nitro-phenyl)-1-cyclopropanecarboxylic acid 
• 236418-11-4 1-(4-chloro-3-nitro-phenyl)-1-cyclopropanecarboxylic acid 
• 236418-13-6 1-(3-amino-4-methylamino-phenyl)-cyclopropanecarboxylic acid 
• 18910-26-4 2-amino-3-(4-cyano-phenyl)-propionic acid 
• 43229-87-4 3-(4-cyano-phenyl)-2-oxo-propionic acid 
• 72934-37-3 3-(4-chlorophenyl)-1-cyclopropanecarboxylic acid 

Downstream Products

• 777044-08-3 N-{1-[3-(4-carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid ethyl ester 

Relevant articles and documents

Heterocyclic thrombin inhibitors. Part 2: Quinoxalinone derivatives as novel, potent antithrombotic agents

Quinoxalinone derivatives as prototypes of dual thrombin and factor Xa inhibitors have been discovered. Nanomolar inhibition of both coagulation enzymes resulted in very potent antithrombotic activity in vitro.