23681-89-2

Usage

Uses

Used in Fragrance and Flavor Industries:
2,3-Dihydrobenzofuran-6-ol is used as a key ingredient in the fragrance and flavor industries for its natural floral scent, adding a pleasant aroma to various products.
Used in Perfume Production:
In the perfume industry, 2,3-Dihydrobenzofuran-6-ol is used as a fragrance component to create complex and appealing scents, capitalizing on its natural floral notes.
Used in Soap and Beauty Products:
2,3-Dihydrobenzofuran-6-ol is used as a scent enhancer in soaps and other beauty products, contributing to their overall sensory appeal and consumer experience.
Used in Personal Care Products:
2,3-Dihydrobenzofuran-6-ol is also utilized in personal care products, where it serves to provide a pleasant aroma and potentially offer antioxidant and antimicrobial benefits to the formulations.
Used in Essential Oils:
2,3-Dihydrobenzofuran-6-ol is found in essential oils, where it contributes to the overall therapeutic and aromatic profile of these oils, enhancing their use in aromatherapy and other applications.

Upstream product

• 1020947-92-5 6-hydroxy-2,3-dihydrobenzofuran-3-ol 
• 6272-26-0 6-hydroxybenzofuran-3-one 
• 13196-11-7 6-hydroxybenzofuran 
• 52085-14-0 4-benzoxy-salicylaldehyde 

Downstream Products

• 110394-05-3 1-(6-hydroxy-2,3-dihydro-benzofuran-5-yl)-2-(2-methoxy-phenyl)-ethanone 
• 30153-23-2 2-(2-carboxymethoxy-phenyl)-1-(6-hydroxy-2,3-dihydro-benzofuran-5-yl)-ethanone 
• 30153-27-6 1-(6-hydroxy-2,3-dihydro-benzofuran-5-yl)-2-(2-methoxycarbonylmethoxy-phenyl)-ethanone 
• 93011-93-9 1-(6-hydroxy-2,3-dihydro-benzofuran-5-yl)-2-phenyl-ethanone 
• 7647-01-0 hydrogenchloride 
• 1072004-22-8 tert-butyl [5-(2,3-dihydro-1-benzofuran-6-yloxy)-2-nitrophenyl]methylcarbamate 
• 1222555-33-0 7-chloro-1-(diphenylmethyl)-3-hydroxy-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one 
• 1072004-25-1 methyl 3-{[6-(2,3-dihydro-1-benzofuran-6-yloxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate monohydrochloride 
• 1072002-33-5 3-{[6-(2,3-dihydro-1-benzofuran-6-yloxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid 
• 1072004-24-0 methyl 3-[2-({2-[(tert-butoxycarbonyl)(methyl)amino]-4-(2,3-dihydro-1-benzofuran-6-yloxy)phenyl}amino)-2-oxoethoxy]benzoate 
• 1072004-23-9 tert-Butyl [2-amino-5-(2,3-dihydro-1-benzofuran-6-yloxy)phenyl]methylcarbamate 

Relevant academic research and scientific papers

Lewis acid-promoted site-selective cyanation of phenols

An efficient Lewis acid-promoted site-selective electrophilic cyanation of 3-substituted and 3,4-disubstituted phenols has been developed. The cyanation reactions using MeSCN as the cyanating reagent proceeded efficiently to afford a wide range of 2-hydroxybenzonitriles with high efficiency and excellent regioselectivity. This protocol could provide a practical method for the synthesis and modification of biologically active molecules.

Concise synthesis of 6-cyanobenzo[ b ]furan, a useful building block

A new three-step synthesis of 6-cyanobenzo[b]furan (6) was developed, starting from commercially available 6-hydroxybenzo[b]furan-3-one (18). Key steps in this process were the first step, which was the reductive dehydration of 18 to produce 6-hydroxybenzo[b]furan (19), and the last step, which converted the aryl triflate 20 to the aryl cyanide 6 in a palladium-catalyzed cross-coupling protocol. Overall yield for this new synthesis was 49%.

Triarylimidazoles

Compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1, R2and R3are various substituent groups; and one of X1and X2is N or CR′, and the other is NR′ or CHR′ wherein R′ is hydrogen, OH, C1-6alkyl, or C3-7cycloalkyl; or when one of X1and X2is N or CR′ then the other may be S or O; and their use as pharmaceuticals.

Novel benzofuranyl pest retardants

Alkyl ethers of 2,3-dihydrobenzofuran where the alkyl chain may contain branched chains, unsaturated bonds, epoxy bridges, and may be substituted with halo, alkoxy, lower alkenyloxy, or lower alkynyloxy substituents useful in killing and preventing the proliferation of insects and other pests by upsetting their hormone balance.