23690-10-0Relevant articles and documents
GSH- and pH-responsive drug delivery system constructed by water-soluble pillar[5]arene and lysine derivative for controllable drug release
Wu, Xuan,Li, Yan,Lin, Chen,Hu, Xiao-Yu,Wang, Leyong
, p. 6832 - 6835 (2015)
Novel GSH- and pH-responsive supramolecular vesicles constructed by an amphiphilic inclusion complex formed from water-soluble pillar[5]arene and lysine derivative have been successfully developed, which can efficiently encapsulate anticancer drug MTZ and show rapid MTZ-release in a simulated acidic tumor environment with high GSH concentration, and exhibit potent antitumor activity.