84359-61-5

Basic information

• Product Name: 9-(3-Bromopropyl)-9H-carbazole
• Synonyms: 9-(3-Bromopropyl)-9H-carbazole;IN1840, 9H-Carbazole, 9-(3-bromopropyl)-
• CAS NO: 84359-61-5
• Molecular Formula: C₁₅H₁₄BrN
• Molecular Weight: 288.18236
• Mol File: 84359-61-5.mol
• Article Data: 24

Chemical Properties

• Melting Point: 56 °C
• Appearance: /
• CAS DataBase Reference: 9-(3-Bromopropyl)-9H-carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(3-Bromopropyl)-9H-carbazole(84359-61-5)
• EPA Substance Registry System: 9-(3-Bromopropyl)-9H-carbazole(84359-61-5)

Safety Data

• Hazardous Substances Data: 84359-61-5(Hazardous Substances Data)

Usage

General Description

9-(3-Bromopropyl)-9H-carbazole is a chemical compound that belongs to the group of carbazoles, which are heterocyclic organic compounds containing a three-ring structure. The molecular formula of this compound is C15H14BrN which denotes it is composed of 15 carbon atoms, 14 hydrogen atoms, one bromine atom, and one nitrogen atom. The physical properties of this particular chemical are not commonly reported, suggesting that it could potentially be an infrequently researched or synthesized compound. Due to the presence of the carbazole group, which is well-known for its uses in pharmaceuticals and in materials science, including in the production of polymers and dyes, it might have potential applications in these fields. However, the specific use, safety, and toxicity information for 9-(3-Bromopropyl)-9H-carbazole is not widely available and would need to be confirmed by empirical studies.

Upstream product

• 86-74-8 9H-carbazole 
• 109-64-8 1,3-dibromo-propane 
• 109-70-6 1.3-chlorobromopropane 
• 251907-44-5 9-[3-(tetrahydro-pyran-2-yloxy)-propyl]-9H-carbazole 
• 54060-74-1 3-(9H-carbazol-9-yl)propan-1-ol 

Downstream Products

• 3998-04-7 9-allyl-9H-carbazole 
• 850741-42-3 methyl (2S,4R)-1-[3-(carbazol-9-yl)-1-propyl]-4-hydroxy-pyrrolidine-2-acetate 
• 184845-24-7 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-tolyl)piperidin-4-ol hydrochloride 
• 742037-29-2 9-[3-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]propyl]carbazole 
• 59135-37-4 N-(3-carbazol-9-yl-propyl)-acrylamide 
• 915376-48-6 diethyl (3-(9H-carbazol-9-yl)propyl)phosphonate 
• 1229705-77-4 1-(3-carbazol-9-ylpropyl)-3-[1-(4-methoxybenzyl)-1H-tetrazol-5-yl]azetidin-3-ol 
• 1229705-76-3 1-(3-carbazol-9-ylpropyl)-3-(4-methoxyphenyl)azetidin-3-ol 
• 1352655-14-1 tert-butyl 1-((9-(3-(dimethylamino)propyl)-9H-carbazol-3-yl)methyl)piperidin-3-ylcarbamate 
• 1388758-11-9 9-(3-(naphthalen-2-ylthio)propyl)-9H-carbazole 
• 1440956-46-6 3-(9H-carbazol-9-yl)propylboronic acid 
• 1012857-59-8 9-(4,4,4-trifluorobutyl)-9H-carbazole 
• 1440956-00-2 9-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)-9H-carbazole 
• 1547068-64-3 3-(9H-carbazol-9-yl)-N-(4-fluorobenzyl)propan-1-amine 

Relevant articles and documents

New classes of carbazoles as potential multi-functional anti-Alzheimer's agents

Multi-Target approach is particularly promising way to drug discovery against Alzheimer's disease. In the present study, we synthesized a series of compounds comprising the carbazole backbone linked to the benzyl piperazine, benzyl piperidine, pyridine, quinoline, or isoquinoline moiety through an aliphatic linker and evaluated as cholinesterase inhibitors. The synthesized compounds showed IC50 values of 0.11–36.5 μM and 0.02–98.6 μM against acetyl- and butyrylcholinesterase (AChE and BuChE), respectively. The ligand-protein docking simulations and kinetic studies revealed that compound 3s could bind effectively to the peripheral anionic binding site (PAS) and anionic site of the enzyme with mixed-type inhibition. Compound 3s was the most potent compound against AChE and BuChE and showed acceptable inhibition potency for self- and AChE-induced Aβ1-42 aggregation. Moreover, compound 3s could significantly protect PC12 cells against H2O2-induced toxicity. The results suggested that the compounds 3s could be considered as a promising multi-functional agent for further drug discovery development against Alzheimer's disease.

A simple but effective fluorescent probe for the detection of bisulfite

A new fluorescence probe (PML) for sensing HSO3- was developed based on a Michael addition reaction mechanism. The probe was composed of carbazole and 2-(3-cyano-4,5,5-trimethylfuran-2(5H)-ylidene)malononitrile moieties and can be easily synthesized. The carbazole-based probe can selectively detect HSO3- and shows good sensitivity with the limit of detection of 2.08 × 10-6 M in a PBS:DMF = 1:1 buffer solution. Upon addition of HSO3-, the intense fluorescence of the probe was quenched, and the color markedly changed from red to colorless. In addition, the probe can be used to detect HSO3- in dry white wine.

A organic long afterglow compound and its preparation method and application (by machine translation)

The invention relates to a kind of organic long afterglow compound and its preparation method and application, the organic long afterglow compounds have the formula (I) indicated by the structure, the present invention provides compounds of formula (I) have shown long afterglow compound long service life, and different structure sub compound of different service life, various colors, when the stop of the excitation light source is illuminated, its emitted light by the fluorescence can be realized to the phosphorescent color change, after gradually reducing the brightness, the nature of the time-resolved technology can be combined with the four-dimensional coding, a large amount of information storage and information encryption. (by machine translation)