2372-88-5

Usage

Uses

Used in Pharmaceutical Industry:
Diaminomethane is used as an intermediate in the synthesis of FK-506 3'-Methyl Ether (F370010), a fermentation process impurity. It plays a crucial role in the production of Tacrolimus (F370000), an immunosuppressive drug used to prevent organ rejection in transplant patients. The compound is formed during the fermentation process using a strain of Streptomyces Tsukubaensis.
Additionally, diaminomethane can be used in the synthesis of other pharmaceutical compounds, agrochemicals, and specialty chemicals, depending on the specific requirements of the industry. Its applications may vary, but its primary use lies in its role as a chemical intermediate in the production of various products.

Upstream product

• 50-00-0 formaldehyd 
• 75-11-6 diiodomethane 
• 6921-98-8 Bis(formamido)methane 
• 15441-63-1 N,N'-methylenebis 
• 57461-31-1 hippuroyl azide 
• 7732-18-5 water 
• 7664-93-9 sulfuric acid 
• 463-52-5 formamidine 
• 17356-08-0 thiourea 

Downstream Products

• 1575-94-6 N,N'-methylenebisbenzamide 
• 53597-69-6 (1,3,5-triaza-7-phosphaadamantane) 
• 17303-89-8 2-methyl-2H-thieno[3,2-d][1,2,3]diazaborinin-1-ol 
• 17303-94-5 2-methyl-2H-thieno[3,4-d][1,2,3]diazaborinin-1-ol 
• 17303-85-4 2-methyl-2H-thieno[2,3-d][1,2,3]diazaborinin-1-ol 
• 220461-44-9 [2-Chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-(3-dimethylaminomethyl-5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone 

Relevant academic research and scientific papers

Competitive effects of S-containing catalyst poisons on the UPD of H in relation to H2 evolution kinetics and OPD of H at Pt

The competitive adsorption of catalyst poisons and adsorbed H is of interest in relation to their effects in promoting H absorption into transition metals. The capacity of three sulfur-containing compounds, thiourea, L-cysteine and 2,2′-diethanolsulfide (DES), to block H adsorption at Pt electrodes in both the underpotential deposition (UPD) and overpotential deposition (OPD) regions is studied. Differences in the rates of adsorption (cysteine and DES cysteine and DES) are shown to play important roles in the extent to which the poison, P, can block the UPD of H and modify the Tafel relationship for the hydrogen evolution reaction (HER). The relative H blocking, due to poison coverage, θP, is measured by means of cyclic voltammetry and potential-relaxation transient experiments. Measurements of rates of the HER as a function of overpotential are also made utilizing steady-state techniques. It is shown that, for θP of cysteine and DES 2 evolution takes place, θP varies with potential according to an isotherm determined by the kinetics of hydrogenation and/or desorption of the poison.

Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety

Reactive dyes of the formula STR1 in which D is the radical of an organic dye of the monoazo, polyazo, metal complex azo, anthraquinone, phthalocyanine, formazan, azomethine, dioxazine, phenazine, stilbene, triphenylmethane, xanthene, thioxanthrone, nitroaryl, naphthoquinone, pyrenequinone or perylenetetracarbimide series, R is hydrogen or substituted or unsubstituted C1-4 -alkyl, X is a substituent which is detachable as an anion, B is a radical of the formula STR2 R1 and R2, independently of each other, are hydrogen or substituted or unsubstituted C1-4 -alkyl or phenyl, A is a substituted or unsubstituted aliphatic or aromatic bridge member, Y is a --CO--Z or --SO2 --Z radical, Z is an aliphatic, aromatic or heterocyclic reactive radical, and n is 1 or 2, are suitable for dyeing or printing cellulose-containing and nitrogen-containing materials and in high dyeing yield produce dyeings and prints having good fastness properties.