23731-55-7

Upstream product

• 1817-95-4 4-methoxy-benzo[1,3]dioxole 
• 68-12-2 N,N-dimethyl-formamide 
• 93-61-8 N-methyl-N-phenylformamide 
• 2144-08-3 2,3,4-trihydroxybenzylaldehyde 
• 934-00-9 3-methocycatechol 
• 159263-87-3 2-acetyloxy-3-methoxy-6-bromobenzaldehyde 
• 61559-82-8 1-Bromo-2,3dihydroxy-4methoxy-benzene 
• 7150-01-8 2-acetoxy-3-methoxybenzaldehyde 
• 20035-41-0 6-bromo-2-hydroxy-3-methoxybenzaldehyde 
• 10025-87-3 trichlorophosphate 
• 61535-22-6 1-bromo-4-methoxy-2,3-methylenedioxybenzene 
• 4055-69-0 2,3-dihydroxy-4-methoxybenzaldehyde 
• 74-95-3 1,1-dibromomethane 
• 126355-81-5 trans-4-methoxy-2,3-methylenedioxycinnamaldehyde 

Downstream Products

• 134745-78-1 [2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-(7-methoxy-benzo[1,3]dioxol-4-ylmethyl)-amine 
• 134776-83-3 8-[2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-4-methoxy-6-methyl-6-methylsulfanyl-8,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinolin-7-one 
• 134745-79-2 8-[2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-4-methoxy-6-methylsulfanyl-8,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinolin-7-one 
• 134745-80-5 8-[2-(3,4-Dimethoxy-phenyl)-ethyl]-4-methoxy-6-methyl-8,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinolin-7-one 
• 197070-03-4 7-methoxy-1-(3,4-dimethoxybenzyl)-2-methyl-5,6-methylenedioxy-1,2-dihydroisoquinoline 
• 197069-98-0 7-methoxy-1-(3,4-dimethoxybenzyl)-5,6-methylenedioxy-1,2,3,4-tetrahydroisoquinoline 
• 197070-00-1 6-(3,4-Dimethoxy-benzyl)-4-methoxy-[1,3]dioxolo[4,5-f]isoquinoline 
• 104958-32-9 N-(4-methoxy-2,3-methylenedioxyphenethyl)-3,4-dimethoxyphenylacetamide 
• 1369266-51-2 C₂₀H₂₀O₈ 
• 104958-28-3 (3,4-Dimethoxy-phenyl)-(4-methoxy-8,9-dihydro-[1,3]dioxolo[4,5-f]isoquinolin-6-yl)-methanone 
• 104958-27-2 (3,4-Dimethoxy-phenyl)-(4-methoxy-[1,3]dioxolo[4,5-f]isoquinolin-6-yl)-methanone 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 10-benzyloxy-Narciclasine

A chemoenzymatic convergent synthesis of 10-benzyloxy narciclasine from bromobenzene was accomplished in 16 steps. The key transformations included toluene dioxygenase-mediated hydroxylation, nitroso Diels-Alder reaction and intramolecular Heck cyclization. The unnatural derivative of narciclasine was subjected to biological evaluation and its activity was compared to other C-10 and C-7 compounds prepared previously.

THE SYNTHESIS OF 6-METHOXY-7,8-METHYLENEDIOXYISOQUINOLINE DERIVATIVES

Several new 6-methoxy-7,8-methylenedioxyisoquinolines were synthesized starting from 4-methoxy-2,3-methylenedioxybenzaldehyde.

PREPARATION OF 2-METHOXY-3,4-METHYLENEDIOXYBENZALDEHYDE (CROWEACIN ALDEHYDE) FROM PYROGALLOL

2-Methoxy-3,4-methylenedioxybenzaldehyde (croweacin aldehyde) of high purity was prepared in 55percent overall yield from pyrogallol.

The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 21. A Mild Process For The Preparation of 10-Alkyl-9-acridanones And It's Application To The Synthesis of Acridone Alkaloids

10-Substituted-9-acridanones are readily prepared by the reaction of the corresponding isatoic anhydride with the lithium enolate of 2-cyclohexen-1-one.The initially formed product, the 1,2-dihydroacridone need not be purified but can be aromatized directly with DDQ to the desired acridone.This methodology is applicable to the synthesis of acridone natural products.Two alkaloids, 1,2,3-trimethoxy-10-methylacridone (9) and evoxanthine (10), were prepared from 4,5,6-trimethoxy-N-methylisatoic anhydride and 6-methoxy-4,5-methylenedioxy-N-methylisatoic anhydride respectively.In these trioxygenated systems, palladium-on-charcoal must be used to aromatize the penultimate intermediate.

SEARCH FOR METHODS OF SYNTHESIZING 1,9,10- TRIMETHOXY-2,3-METHYLENEDIOXYAPORPHINE.

Several possible methods of obtaining 4-methoxy-2,3-methylenedioxybenzaldehyde have been considered.A method ensuring the synthesis of this aldehyde with a yield of 35-40percent has been developed which consists in the bromination of isovanillin followed by the replacement of the halogen by a hydroxy group and methylation.A number of substituted benzylidene- and benzyltetrahydroisoquinolines have been synthesized.It has been shown that the irradiation of these substances leads to N-dealkylation accompanied by oxidative processes.

Synthesis of the Yeast Antioxidant Benzofuran and Analogues

2-(6-Hydroxy-2-methoxy-3,4-methylenedioxyphenyl)benzofuran, the active antioxidant which occurs in yeasts, and related 2-arylbenzofurans have been synthesized by a convergent route.The key step involves benzofuran formation by an intramolecular Wittig reaction.