238762-33-9

Basic information

• Product Name: 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt
• Synonyms: 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt;(αR)-α-[[(1,1-DiMethylethyl)aMino]Methyl]-2,2-diMethyl-4H-1,3-benzodioxin-6-Methanol (2S,3S)-2,3-Bis[(4-Methylbenzoyl)oxy]butanedioate
• CAS NO: 238762-33-9
• Molecular Formula: C36H43NO11
• Molecular Weight: 665.72672
• Product Categories: Amines;Aromatics;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 238762-33-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly)
• CAS DataBase Reference: 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt(238762-33-9)
• EPA Substance Registry System: 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt(238762-33-9)

Safety Data

• Hazardous Substances Data: 238762-33-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Protected (R)-Albuterol

Upstream product

• 102293-80-1 2-bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanone 
• 62932-94-9 2-bromo-1-[4-hydroxy-3-(hydroxymethyl)-phenyl]ethanone 
• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 54208-72-9 2-(tert-butylamino)-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxan-6-yl)ethanol 
• 32634-66-5 Di-p-toluoyl-L-tartaric acid 
• 115787-50-3 5-(2-bromoacetyl)-2-hydroxybenzaldehyde 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Levalbuterol intermediate and synthetic method of levalbuterol hydrochloride

The invention provides a levalbuterol intermediate and a levalbuterol hydrochloride synthesis method, and relates to a levalbuterol intermediate and a method for preparing levalbuterol hydrochloride from the intermediate. The method comprises steps as follows: 2-halogenate-1-(2,2-dimelthyl-4-hydrogen-benzo [d][1,3] dioxane)-butanone and organic amine have a Hoffman alkylation reaction to prepare a compound in the formula 2, the structural formula of the compound is shown in the specification, and the compound in the formula 2 is subjected to a reduction reaction, optically pure organic acid resolution and deprotection by hydrochloric acid to obtain levalbuterol hydrochloride. The method does not need processes of protection or deprotection and the like of hydroxyl groups on a benzene ring, protection, deprotection and purification processes are reduced, the synthesis route is short, operation is simple, meanwhile, borane-thioether does not need to be used as a reduction agent, and safety and environmental protection are realized.