23879-15-4

Upstream product

• 3717-24-6 4-chlorobenzaldehyde oxime 
• 104-88-1 4-chlorobenzaldehyde 
• 3848-36-0 4-chlorobenzaldoxime 

Downstream Products

• 21614-47-1 3-(4-chlorophenyl)-5-methyl-1,2,4-oxadiazole 
• 104-88-1 4-chlorobenzaldehyde 
• 74-11-3 para-chlorobenzoic acid 

Relevant academic research and scientific papers

Ceric ammonium nitrate oxidation of aldoximes in aliphatic nitriles as solvents: A new way for synthesis of 1,2,4-oxadiazoles

Oxidation of aromatic aldoximes with one-electron oxidant ceric ammonium nitrate CAN in acetonitrile and propionitrile, has been investigated. Aromatic nitrile oxides, formed in situ, underwent 1,3-cycloaddition with aliphatic nitriles and 5-alkyl-3-aryl-1,2,4-oxadiazoles are produced in moderate to high yields. The mechanism of the reaction based on the transformations of intermediate aldazine di-N-oxides is discussed.

A facile preparation of iminoxy dimers by hydrogen peroxide/peroxidase oxidation of aldoximes

The oxidation of benzaldehyde oximes of the type R-C6H4-CH=NOH (R=H, Me, OMe, Cl) by a hydrogen peroxide/horseradish peroxidase system yields the corresponding dimers of iminoxy radicals (benzaldehyde azines) in high yields.