21614-47-1 Usage
Description
3-(4-Chlorophenyl)-5-methyl-1,2,4-oxadiazole, commonly referred to as CMOD, is a heterocyclic chemical compound characterized by the molecular formula C9H7ClN2O. It is distinguished by the presence of both nitrogen and oxygen in its structure, which endows it with a diverse range of chemical properties and applications.
Uses
Used in Pharmaceutical Synthesis:
3-(4-Chlorophenyl)-5-methyl-1,2,4-oxadiazole is utilized as a building block in the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs, enhancing their therapeutic potential.
Used in Agrochemical and Veterinary Medicine Production:
In the agricultural industry, CMOD serves as a key component in the formulation of pesticides and fungicides. Its chemical properties contribute to the effectiveness of these products in controlling pests and diseases, thereby protecting crops and ensuring food security.
Used in Medicinal Research:
3-(4-Chlorophenyl)-5-methyl-1,2,4-oxadiazole has been the subject of research for its potential anticancer and antibacterial properties. Its ability to target specific biological pathways makes it a promising candidate for the development of novel therapeutic agents.
Used in Chemical Research and Development:
CMOD's unique structure and properties make it a valuable compound in the field of chemical research and development. It can be used to explore new chemical reactions and syntheses, leading to the discovery of innovative materials and compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 21614-47-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,1 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21614-47:
(7*2)+(6*1)+(5*6)+(4*1)+(3*4)+(2*4)+(1*7)=81
81 % 10 = 1
So 21614-47-1 is a valid CAS Registry Number.
21614-47-1Relevant articles and documents
Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles
Wang, Xuetong,Wang, Yin,Liu, Xiaoling,He, Tingshu,Li, Lingli,Wu, Huili,Zhou, Shangjun,Li, Dan,Liao, Siwei,Xu, Ping,Huang, Xing,Yuan, Jianyong
supporting information, (2021/10/14)
Imidazole hydrochloride as an additive promotes the reaction of amidoximes and DMA derivatives to generated 3,5-disubstituted-1,2,4-oxadiazoles in low to excellent yields without the use of coupling reagents, oxidants, strong acids or bases and other additives.
Cobalt(III)-Catalyzed Oxadiazole-Directed C-H Activation for the Synthesis of 1-Aminoisoquinolines
Yang, Fan,Yu, Jiaojiao,Liu, Yun,Zhu, Jin
supporting information, p. 2885 - 2888 (2017/06/07)
Aromatic heterocycles have been identified as effective directing groups (DGs) in C-H functionalization but can be retained as undesired bulky substituents in the final products. Herein, we report a Co(III)-catalyzed 1-aminoisoquinoline synthesis strategy based on oxadiazole-directed aromatic C-H coupling with alkynes and a subsequent redox-neutral C-N cyclization reaction. This labile N-O bond-based protocol has allowed the toleration of a broad range of functional groups.
Iron(III) Chloride/l-Proline as an Efficient Catalyst for the Synthesis of 3-Substituted 1,2,4-Oxadiazoles from Amidoximes and Triethyl Orthoformate
Kaboudin, Babak,Kazemi, Foad,Pirouz, Maryam,Khoshkhoo, Aysan Baharian,Kato, Jun-Ya,Yokomatsu, Tsutomu
, p. 3597 - 3602 (2016/10/18)
A general, facile, and efficient method is presented for the synthesis of 3-substituted 1,2,4-oxadiazoles from amidoximes and triethyl orthoformate. The procedure employs an iron(III) chloride/l-proline catalytic system and the 3-substituted 1,2,4-oxadiaz
