23967-97-7

Basic information

• Product Name: 3-AMINO-4-METHYLTHIOPHENE
• Synonyms: 3-AMINO-4-METHYLTHIOPHENE;3-ThiophenaMine, 4-Methyl-;4-METHYLTHIOPHEN-3-AMINE(WXG00499)
• CAS NO: 23967-97-7
• Molecular Formula: C₅H₇NS
• Molecular Weight: 113.18078
• Mol File: 23967-97-7.mol

Chemical Properties

• Boiling Point: 246.7 °C at 760 mmHg
• Flash Point: 103 °C
• Appearance: /
• Density: 1.161g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.12±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-4-METHYLTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-METHYLTHIOPHENE(23967-97-7)
• EPA Substance Registry System: 3-AMINO-4-METHYLTHIOPHENE(23967-97-7)

Safety Data

• Hazardous Substances Data: 23967-97-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-4-methylthiophene is used as a key intermediate in the synthesis of various pharmaceuticals due to its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-4-methylthiophene serves as a building block for the creation of compounds that can be used in the development of pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in Organic Compounds Synthesis:
3-Amino-4-methylthiophene is utilized as a versatile reactant in the synthesis of a broad spectrum of organic compounds, contributing to the advancement of organic chemistry and the creation of novel molecules with diverse applications.
Used in Materials Science:
3-Amino-4-methylthiophene is employed in materials science research for its electronic and optical properties, potentially leading to the development of new materials with applications in electronics, optoelectronics, and other high-tech fields.

Upstream product

• 616-44-4 3-Methylthiophene 
• 30318-99-1 3-bromo-4-methylthiophene 
• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 
• 23968-18-5 3-amino 4-methylthiophene-2-carboxylic acid 

Downstream Products

• 1246226-70-9 4-methyl-2-p-tolylthiophen-3-ylamine 
• 1246226-59-4 4-methyl-2-(4-trifluoromethylphenyl)-thiophen-3-ylamine 
• 953044-73-0 1-(4-(2-(5-(3-methylthieno[3,2-b]pyridin-7-ylthio)-3-phenoxypyridin-2-ylamino)thiazol-4-yl)piperidin-1-yl)ethanone 
• 953045-90-4 3-methylthieno[3,2-b]pyridin-7-ol 
• 953045-91-5 7-chloro-3-methylthieno[3,2-b]pyridine 
• 24030-00-0 3-amino-4-methylthiophene hydrochloride 
• 1393718-94-9 4-(3-amino-4-methylthiophen-2-yl)benzonitrile 
• 1393718-95-0 2-(4-methoxyphenyl)-4-methylthiophen-3-amine 

Relevant articles and documents

C-H Amination of Arenes with Hydroxylamine

This Letter describes the development of a TiIII-mediated reaction for the C-H amination of arenes with hydroxylamine. This reaction is applied to a variety of electron-rich (hetero)arene substrates, including a series of natural products and pharmaceuticals. It offers the advantages of mild conditions (room temperature), fast reaction rates (30 min), compatibility with ambient moisture and air, scalability, and the use of inexpensive commercial reagents.

Ligandless copper-catalyzed coupling of heteroaryl bromides with gaseous ammonia

A range of different N- and S-containing heterocyclic bromides can be efficiently coupled with gaseous ammonia in the presence of copper(II) acetylacetonate [Cu(acac)2] as catalyst and in the absence of additional ligands. Unstable aminothiophenes and aminobenzothiophenes can be further reacted in situ to afford functionalized derivatives. Copyright

PROCESS FOR PREPARING 4-METHYL-3-THIENYLAMINE HYDROCHLORIDE

This invention is related to a process for preparing 3-amino-4-methylthiophene hydrochloride.

PROCESS FOR PREPARING 2-CHLORO-3N-(2-BENZIMIDAZOLYL)-4-METHYL-3-THIENYLAMINE USEFUL AS A SODIUM/PROTON EXCHANGER TYPE 3 INHIBITOR

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PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL AS SODIUM/PROTON EXCHANGER TYPE 3 INHIBITORS

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