2404-04-8Relevant academic research and scientific papers
Dichlorodimethyl hydantoin: An efficient reagent for one-pot synthesis of CWC-related O,O-dialkyl, N,N-dialkyl phosphoramidates
Gupta, Arvind K.,Dubey, Devendra K.,Kaushik
scheme or table, p. 1641 - 1658 (2009/06/18)
A simple, rapid, economical, and efficient one-pot synthetic method for preparation of O,O-dialkyl, N,N-dialkylphosphoramidates (DADAPs) and phosphates has been developed. Copyright Taylor & Francis Group, LLC.
N,N′-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2): An efficient reagent for the synthesis of chemical weapons convention-related dialkyl-N,N-dialkylphosphoramidates from dialkylphosphites
Gupta, Arvind K.,Pardasani, Deepak,Gupta, Hemendra K.,Dubey, Devendra K.
, p. 879 - 882 (2008/09/16)
The present paper describes the one-pot synthesis of dialkyl N,N-dialkylphosphoramidates (DADAP) from dialkylphosphites and dialkylamines using N,N?-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2) as chlorinating reagent. DADAP belong to the schedule 2.B.6 category of the Chemical Weapons Convention (CWC), as they are the important markers of the chemical warfare agent tabun and its analogues. The study was undertaken to develop the spectral database of DADAP for verification of CWC. The reported synthetic strategy can be adopted to rapidly synthesize several analogues of DADAP during official proficiency tests. CSIRO 2007.
ON THE REACTION OF BENZOTHIAZOL-2-YL SULPHENAMIDES WITH PHOSPHITES
Brownbridge, P.,Jowett, I. C.
, p. 311 - 318 (2007/10/02)
A study of the synthesis of phosphoramidates from phosphites and benzothiazol-2-yl-sulphenamides, indicates that a quinquecovalent phosphorane is an intermediate.Since the initial step in this reaction does not involve attack of phosphorus on nitrogen, it is unlikely that these sulphenamides will act as electrophilic aminating agents towards non-phosphorus nucleophiles.An efficient new method for preparing benzothiazol-2-yl-sulphenamides is reported.
