240405-26-9Relevant academic research and scientific papers
Total synthesis of (+)-(2S,3R)-piscidic acid via catalytic asymmetric dihydroxylation of a trisubstituted olefin
Toshima, Hiroaki,Saito, Masatoshi,Yoshihara, Teruhiko
, p. 964 - 967 (2007/10/03)
(+)-(2S,3R)-Piscidic acid was efficiently synthesized with high optical purity (90% e.e.) via Sharpless catalytic asymmetric dihydroxylation of a trisubstituted olefin in only 6 steps from commercially available 4-hydroxyphenylpyruvic acid as the starting
Total syntheses of all four stereoisomers of piscidic acid via catalytic asymmetric dihydroxylation of (Z)- and (E)-trisubstituted olefins
Toshima, Hiroaki,Saito, Masatoshi,Yoshihara, Teruhiko
, p. 1934 - 1941 (2007/10/03)
All four stereoisomers of (2S, 3R)-(+)-piscidic acid were synthesized with high optical purity via Sharpless catalytic asymmetric dihydroxylation of (Z)- and (E)-trisubstituted olefins in 6 steps from (4-hydroxyphenyl)pyruvic acid. The Wittig reaction of
