24107-62-8

Upstream product

• 109-65-9 1-bromo-butane 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 618-31-5 benzylidene dibromide 
• 51592-02-0 o-amino-N-n-butylaminobenzene 
• 98-88-4 benzoyl chloride 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 815581-69-2 N-(n-butyl)-2-(2-bromophenyl)-benzimidazole 

Relevant academic research and scientific papers

Simultaneous modification of N-alkyl chains on cyclometalated and ancillary ligands of cationic iridium(III) complexes towards efficient piezochromic luminescence properties

In this study, we have designed and synthesized a series of multifunctional cationic iridium(iii) complexes with different lengths of N-alkyl chains on 2-phenyl-1H-benzimidazole-based cyclometalated ligands and phenyl-pyridine type ancillary ligands. The

Benzimidazole nitrogen-directed, regiocontrolled, lithiation of ferrocenyl- and phenyl-N-n-butylbenzimidazoles

2-Ferrocenyl- and 2-phenyl-N-n-butylbenzimidazoles were synthesized to evaluate the influence of the benzimidazole functional group upon their directed lithiation. The regiochemistry of lithiation was studied, as well as the effect of stabilization of the

Effect of alkyl chain length on piezochromic luminescence of iridium(III)-based phosphors adopting 2-phenyl-1H-benzoimidazole type ligands

In this work, a series of luminescent cationic iridium(iii) complexes containing 2-phenyl-1H-benzimidazole-type ligands modified with n-alkyl chains of various lengths have been successfully synthesized and characterized. Their photophysical and electroch

1,2-Disubstituted Benzimidazoles by the Iron Catalyzed Cross-Dehydrogenative Coupling of Isomeric o-Phenylenediamine Substrates

Benzimidazoles are common in nature, medicines, and materials. Numerous strategies for preparing 2-arylbenzimidazoles exist. In this work, 1,2-disubstituted benzimidazoles were prepared from various mono- and disubstituted ortho-phenylenediamines (OPD) by iron-catalyzed oxidative coupling. Specifically, O2 and FeCl3·6H2O catalyzed the cross-dehydrogenative coupling and aromatization of diarylmethyl and dialkyl benzimidazole precursors. N,N′-Disubstituted-OPD substrates were significantly more reactive than their N,N-disubstituted isomers, which appears to be relative to their propensity for complexation and charge transfer with Fe3+. The reaction also converted N-monosubstituted OPD substrates to 2-substituted benzimidazoles; however, electron-poor substrates produce 1,2-disubstituted benzimidazoles by intermolecular imino-transfer. Kinetic, reagent, and spectroscopic (UV-vis and EPR) studies suggest a mechanism involving metal-substrate complexation, charge transfer, and aerobic turnover, involving high-valent Fe(IV) intermediates. Overall, comparative strategies for the relatively sustainable and efficient synthesis of 1,2-disubstituted benzimidazoles are demonstrated.

Novel 1,3-benzodiazole beta-oxime ester compound and composition comprising the same

The present invention relates to a novel 1,3-benzodiazole beta-oxime ester compound, and more specifically, to a novel 1,3-benzodiazole beta-oxime ester compound, represented by chemical formula 1, and a composition comprising the same. In chemical formula 1, R_1, R_2, R_3, and R_4 are the same as defined in the detailed description of the invention.COPYRIGHT KIPO 2018

An efficient strategy for N-alkylation of benzimidazoles/imidazoles in SDS-aqueous basic medium and N-alkylation induced ring opening of benzimidazoles

A sustainable route for the N-1 alkylation of imidazole and benzimidazole derivatives has been developed under volatile organic solvent free condition in alkaline water-SDS system. Incorporation of SDS in the reaction medium enhances the reaction rate by suppressing the solubility issue that arises for different substrates. This method provides high yield of the alkylated product in a shorter reaction time. For reactive alkyl halides reaction proceeds at ambient temperature whereas in the cases of less reactive alkyl halides require 55–60 °C to complete alkylation process. N-alkylation induced ring opening of the heterocyclic ring in benzimidazole derivatives to multifunctional aromatic compounds were noticed at 60 °C when more than two equivalents of alkyl halide was used.

One-pot synthesis of benzimidazoles from gem-dibromomethylarenes using o-diaminoarenes

A one-pot synthesis of benzimidazoles from gem-dibromomethylarenes is described. The reaction shows the method to prepare a variety of benzimidazole analogues with excellent yield.