241139-32-2

Basic information

• Product Name: (R)-5-METHOXYMETHYL-2-OXAZOLIDINONE
• Synonyms: (R)-5-(MethoxyMethyl)oxazolidin-2-one
• CAS NO: 241139-32-2
• Molecular Formula: C5H9NO3
• Molecular Weight: 131.13
• Mol File: 241139-32-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-5-METHOXYMETHYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-METHOXYMETHYL-2-OXAZOLIDINONE(241139-32-2)
• EPA Substance Registry System: (R)-5-METHOXYMETHYL-2-OXAZOLIDINONE(241139-32-2)

Safety Data

• Hazardous Substances Data: 241139-32-2(Hazardous Substances Data)

Usage

General Description

(R)-5-Methoxymethyl-2-oxazolidinone is a chemical compound that belongs to the oxazolidinone class of compounds. It is a stereochemically pure form of the molecule, meaning that all of its constituent atoms are arranged in a specific configuration. (R)-5-METHOXYMETHYL-2-OXAZOLIDINONE is often used as a chiral auxiliary in organic synthesis, where it helps to control the stereochemical outcomes of chemical reactions. It is also employed as a building block in the synthesis of various pharmaceuticals and other bioactive molecules. The (R)-5-Methoxymethyl-2-oxazolidinone has a wide range of applications due to its unique stereochemical properties and versatile reactivity.

Upstream product

• 40492-31-7 4-methoxymethyl-1,3-dioxolan-2-one 
• 51-79-6 urethane 
• 67-56-1 methanol 
• 113420-81-8 (5S)-5-(methanesulfonyloxymethyl)oxazolidin-2-one 
• 598-55-0 methyl carbamate 
• 64491-70-9 R(-)-glycidyl methyl ether 
• 37317-01-4 cerium monofluoride 
• 135682-18-7 (S)-4-(methoxymethyl)-1,3-dioxolan-2-one 
• 930-37-0 glycidyl methyl ether 
• 622-46-8 carbamic acid phenyl ester 

Relevant articles and documents

QUINAZOLINE COMPOUND FOR EGFR INHIBITION

Disclosed is a novel quinazoline compound. Specifically, disclosed are a compound represented by the formula (I) and a pharmacologically acceptable salt.

Aluminium-Catalysed Oxazolidinone Synthesis and their Conversion into Functional Non-Symmetrical Ureas

An efficient and practical aluminium-catalysed approach towards a range of functional oxazolidinones is reported. The method is based on cheap and readily available starting materials including terminal and internal (bicyclic) epoxides and phenyl carbamate. The oxazolidinones serve as highly useful synthons for the high yield preparation of non-symmetrical ureas by nucleophilic ring-opening affording the targeted urea compounds with excellent functional group diversity, high regioselectivity and isolated yields up to >99%.

Process for preparing optically active oxazolidinone derivative

Disclosed is a process for preparing an optically active oxazolidinone derivative comprising allowing hydrazine to react on an optically active ester having a hydroxyl group at the 3-position which is represented by formula (II): wherein R1represents a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, a methoxymethyl group, a benzyloxymethyl group, a benzyloxycarbonylaminomethyl group which may have a substituent or substituents on the benzene ring thereof, an acylaminomethyl group having 3 to 10 carbon atoms, or an alkyloxycarbonylaminomethyl group having 3 to 6 carbon atoms; R2and R3, which may be the same or different, each represent a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, an acetylaminomethyl group, a benzoylaminomethyl group, or a benzyl group; and * indicates an asymmetric carbon atom, and subjecting the resulting hydrazide to Curtius rearrangement.