24122-32-5

Basic information

• Product Name: 4(3H)-Quinazolinone, 3-(4-bromophenyl)-
• CAS NO: 24122-32-5
• Molecular Formula: C14H9BrN2O
• Molecular Weight: 301.142
• Mol File: 24122-32-5.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 3-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 3-(4-bromophenyl)-(24122-32-5)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 3-(4-bromophenyl)-(24122-32-5)

Safety Data

• Hazardous Substances Data: 24122-32-5(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 50735-55-2 2-amino-N-(4-bromophenyl)benzamide 
• 118-92-3 anthranilic acid 
• 122-51-0 orthoformic acid triethyl ester 
• 106-40-1 4-bromo-aniline 
• 149-73-5 trimethyl orthoformate 
• 201230-82-2 carbon monoxide 
• 615-43-0 2-iodophenylamine 
• 118-48-9 isatoic anhydride 
• 68-12-2 N,N-dimethyl-formamide 
• 91-56-5 indole-2,3-dione 
• 119072-55-8 tert-butylisonitrile 
• 123-91-1 1,4-dioxane 
• 107-21-1 ethylene glycol 

Downstream Products

• 2401-10-7 3-(4'-Bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 1788-95-0 3-(4-bromophenyl)-2-methylquinazolin-4(3H)-one 
• 20865-90-1 1-Chloroacetyl-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 84770-75-2 3-(4-Bromo-phenyl)-1-(2-morpholin-4-yl-propionyl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-72-9 1-(β-Morpholinopropionyl)-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 84770-76-3 3-(4-Bromo-phenyl)-1-(2-piperidin-1-yl-propionyl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-73-0 1-(β-Piperidinolpropionyl)-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 84770-77-4 1-(α-Diethylaminopropionyl)-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquiazolin-4-one 
• 84770-71-8 1-(β-Methoxypropionyl)-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 84770-74-1 3-(4-Bromo-phenyl)-1-(2-methoxy-propionyl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-69-4 3-(4-Bromo-phenyl)-1-(3-chloro-propionyl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-70-7 3-(4-Bromo-phenyl)-1-(2-bromo-propionyl)-2,3-dihydro-1H-quinazolin-4-one 

Relevant articles and documents

Aiding the versatility of simple ammonium ionic liquids by the synthesis of bioactive 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinone derivatives

Simple ammonium ionic liquids [ILs] are efficient, green, environmentally friendly catalysts in promoting the Biginelli condensation reaction, Hantzsch reaction and Niementowski reaction to afford 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinone derivatives respectively by eliminating the need for harmful volatile organic solvents. These [ILs] are air and water stable, easy to prepare and cost-effective. The effects of the anions and cations present in [IL] on reactions were investigated. The results clearly indicated that the Biginelli condensation reaction, Hantzsch reaction and Niementowski reaction were heavily influenced by the acidity of [IL], and among various ammonium ionic liquids, [Et3NH][HSO4] showed the best catalytic activity. Furthermore, [IL] could be easily separated and reused with a slight loss of its activity. This technique provided a good alternative way for the industrial synthesis of 1,2,3,4-tetrahydropyrimidinones, 2-aminothiazoles and quinazolinones. The present processes are eco-friendly methods for the synthesis of these derivatives authenticated by several green parameters, namely,E-factor, process mass intensity, reaction mass efficiency, atom economy, and carbon efficiency.

Copper-Catalyzed Oxidative Cyclization of 2-Aminobenzamide Derivatives: Efficient Syntheses of Quinazolinones and Indazolones

A simple copper-catalyzed assembly to formulate quinazolinone and indazolone derivatives in a single protocol manner is reported. These transformations are based on the fact that DMF can serve as a reaction solvent and one carbon synthon for the construct

Transition-metal and oxidant-free approach for the synthesis of diverse N-heterocycles by TMSCl activation of isocyanides

A highly efficient TMSCl-mediated addition of N-nucleophiles to isocyanides has been achieved. This transition-metal and oxidant-free strategy has been applied to the construction of various N-heterocyles such as quinazolinone, benzimidazole and benzothiazole derivatives by the use of distinct amino-based binucleophiles. The notable feature of this protocol includes its mild reaction condition, broad functional group tolerance and excellent yield. This journal is