24124-03-6 Usage
Description
Diethyl isopropylbenzyloxymalonate, also known as 2-Isopropyl-2-(benzyloxy)-propanedioic acid 1,3-diethyl ester, is a light yellow oil with unique chemical properties. It is a key intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Diethyl isopropylbenzyloxymalonate is used as an intermediate in the synthesis of (+)-Lysergic acid and α-Ergocryptine (E597500), which are important compounds with potential applications in the treatment of various medical conditions.
Used in Organic Synthesis:
Diethyl isopropylbenzyloxymalonate is used as a versatile building block in the preparation of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for various synthetic transformations, making it a valuable asset in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 24124-03-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,2 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 24124-03:
(7*2)+(6*4)+(5*1)+(4*2)+(3*4)+(2*0)+(1*3)=66
66 % 10 = 6
So 24124-03-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H24O5/c1-5-20-15(18)17(13(3)4,16(19)21-6-2)22-12-14-10-8-7-9-11-14/h7-11,13H,5-6,12H2,1-4H3
24124-03-6Relevant articles and documents
Lipase-catalyzed synthesis of ethyl (R)-2-benzyloxy-2-isopropylhydrogenmalonate: A useful combination of chemical synthesis with enzymatic methods
Ding, Jing,Yang, Zhijun,Zhao, Yu,Fang, Weizhen,Lu, Qun
, p. 763 - 767 (2019/04/29)
Ethyl (R)-2-benzyloxy-2-isopropylhydrogenmalonate is a key intermediate for the synthesis of the side chain in ergopeptines. In this work, we adopted a method to prepare enantiomeri-cally pure title monoester via immobilized Candida antarctica lipase B (Novozym 435)-catalyzed hydrolysis of the corresponding diester.
The synthesis of alkaloids of the ergotoxin group. 70. Section on ergot alkaloids
Stadler,Guttmann,Hauth,Huguenin,Sandrin,Wersin,Willems,Hofmann
, p. 1549 - 1564 (2007/10/04)
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