60807-00-3

Basic information

• Product Name: diethyl 2-(benzoyloxy)-2-isopropylmalonate
• Synonyms: diethyl 2-(benzoyloxy)-2-isopropylmalonate
• CAS NO: 60807-00-3
• Molecular Weight: 322.358
• Mol File: 60807-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 2-(benzoyloxy)-2-isopropylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(benzoyloxy)-2-isopropylmalonate(60807-00-3)
• EPA Substance Registry System: diethyl 2-(benzoyloxy)-2-isopropylmalonate(60807-00-3)

Safety Data

• Hazardous Substances Data: 60807-00-3(Hazardous Substances Data)

Upstream product

• 759-36-4 diethyl isopropylmalonate 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 24182-47-6 (+)-isopropylbenzyloxymalonic acid monoethyl ester 
• 24124-03-6 isopropylbenzyloxymalonic acid diethyl ester 
• 24124-04-7 diethyl 2-hydroxy-2-isopropylmalonate 
• 29542-26-5 (-)-isopropylbenzyloxymalonic acid monoethyl ester 

Relevant articles and documents

Lipase-catalyzed synthesis of ethyl (R)-2-benzyloxy-2-isopropylhydrogenmalonate: A useful combination of chemical synthesis with enzymatic methods

Ethyl (R)-2-benzyloxy-2-isopropylhydrogenmalonate is a key intermediate for the synthesis of the side chain in ergopeptines. In this work, we adopted a method to prepare enantiomeri-cally pure title monoester via immobilized Candida antarctica lipase B (Novozym 435)-catalyzed hydrolysis of the corresponding diester.