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Benzenemethanol, 3,5-bis(phenylmethoxy)-, methanesulfonate is a complex organic compound with the chemical formula C20H22O4S. It is a derivative of benzenemethanol, featuring two phenylmethoxy groups attached at the 3 and 5 positions of the benzene ring. The compound is characterized by its aromatic structure and the presence of a methanesulfonate group, which contributes to its solubility and reactivity. This chemical is primarily used in the synthesis of various pharmaceuticals and organic compounds due to its unique functional groups and structural properties.

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  • 80457-61-0 Structure
  • Basic information

    1. Product Name: Benzenemethanol, 3,5-bis(phenylmethoxy)-, methanesulfonate
    2. Synonyms:
    3. CAS NO:80457-61-0
    4. Molecular Formula: C22H22O5S
    5. Molecular Weight: 398.48
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 80457-61-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzenemethanol, 3,5-bis(phenylmethoxy)-, methanesulfonate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzenemethanol, 3,5-bis(phenylmethoxy)-, methanesulfonate(80457-61-0)
    11. EPA Substance Registry System: Benzenemethanol, 3,5-bis(phenylmethoxy)-, methanesulfonate(80457-61-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 80457-61-0(Hazardous Substances Data)

80457-61-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 80457-61-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,4,5 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 80457-61:
(7*8)+(6*0)+(5*4)+(4*5)+(3*7)+(2*6)+(1*1)=130
130 % 10 = 0
So 80457-61-0 is a valid CAS Registry Number.

80457-61-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methanesulfonyl 3,5-dibenzyloxybenzyl alcohol

1.2 Other means of identification

Product number -
Other names 3,5-bis(benzyloxy)benzyl mesylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80457-61-0 SDS

80457-61-0Relevant articles and documents

New glucocerebrosidase inhibitors by exploration of chemical diversity of N -substituted aminocyclitols using click chemistry and in situ screening

Díaz, Lucía,Casas, Josefina,Bujons, Jordi,Llebaria, Amadeu,Delgado, Antonio

supporting information; experimental part, p. 2069 - 2079 (2011/06/10)

A library of aminocyclitols derived from CuAAC reaction between N-propargylaminocyclitol 4 and a series of azides [1′25] is described and tested against GCase. Azides have been chosen from a large collection of potential candidates that has been filtered

Dendrimer analogues of linear molecules to evaluate energy and charge-transfer properties

Nantalaksakul, Arpornrat,Dasari, Raghunath Reddy,Ahn, Tai-Sang,Al-Kaysi, Rabih,Bardeen, Christopher J.,Thayumanavan

, p. 2981 - 2984 (2007/10/03)

We have designed and synthesized difunctionalized dendrimers containing two donors in the periphery and an acceptor at the core to serve as scaffolds for comparison with linear analogues to investigate the advantage of dendritic scaffolds for energy and c

The first total synthesis of SB87-Cl and pestalone, novel bioactive benzophenone natural products

Iijima, Daisuke,Tanaka, Daisuke,Hamada, Motoko,Ogamino, Takahisa,Ishikawa, Yuichi,Nishiyama, Shigeru

, p. 5469 - 5471 (2007/10/03)

SB87-Cl 1, an inhibitor of testosterone-5α-reductase, and pestalone 2 exhibiting effective antimicrobial activity against MRSA (MIC=37ng/mL) and VRE (MIC=78ng/mL), were novel bioactive benzophenone natural products. Total synthesis of 1 and 2 has been successfully accomplished. The common synthetic precursor 18 of 1 and 2, was successfully obtained by the coupling of 8 with 12.

5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

-

Page 44, (2010/02/07)

Use of a compound of the formula: wherein R represents a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; X represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -CO-, -CS-, -CR(OR)- or -NR- wherein each of R and R represents a hydrogen atom or a hydrocarbon group which may be substituted, R represents a hydrogen atom or a protective group for a hydroxyl group; m represents an integer of 0 to 3; Y represents an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -NR-, -CONR- or -NRCO- wherein R represents a hydrogen atom or a hydrocarbon group which may be substituted; ring A represents an aromatic ring which may further have 1 to 3 substituents; n represents an integer of 1 to 8; ring B represents a nitrogen-containing 5-membered hetero ring which may further be substituted by an alkyl group; X represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -O-SO2- or -NR- wherein R represents a hydrogen atom or a hydrocarbon group which may be substituted; R represents a hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; W represents a bond or a divalent hydrocarbon residue having 1 to 20 carbon atoms; R represents a group of the formula: -OR (R represents a hydrogen atom or a hydrocarbon group which may be substituted) or -NRR (each of R and R, whether identical or not, represents a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, or an acyl group which may be substituted; R and R may bind together to form a ring); or a salt thereof, for the manufacture of a pharmaceutical preparation for preventing or treating syndrome X.

Mechanistic studies on the biomimetic reduction of tetrahydroxynaphthalene, a key intermediate in melanin biosynthesis

Ichinose,Ebizuka,Sankawa

, p. 192 - 196 (2007/10/03)

1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an aromatic polyketide, serving as a general precursor of fungal melanin. Melanin biosynthesis involves two consecutive deoxygenations of T4HN, consisting of the reduction of a phenolic carbon followed by dehydrat

Alternative convergent and accelerated double-stage convergent approaches towards functionalized dendritic polyethers

Forier,Dehaen

, p. 9829 - 9846 (2007/10/03)

Alternative convergent synthesis strategies for the preparation of dendritic macromolecules, using either mesylate activation or the Mitsunobu reaction, are described. The synthesis can be further accelerated by using a double stage convergent approach. T

DEOXYGENATION IN THE BIOSYNTHESIS OF POLYKETIDES: MECHANISM OF BIOMIMETIC REDUCTION OF TETRAHYDROXYNAPHTHALENE

Ichinose, Koji,Ebizuka, Yutaka,Sankawa, Ushio

, p. 2873 - 2875 (2007/10/02)

A biomimetic synthesis of scytalone, a simple derivative of tetralone, was reinvestigeted using NMR spectroscopy.Scytalone was formed from 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by sodium borohydride reduction only in the presence of sodium methoxi

Drugs derived from Cannabinoids. Part 8. The Synthesis of Side-chain Analogues of Δ6a,10a-Tetrahydrocannabinol

Meltzer, Peter C.,Dalzell, Haldean C.,Razdan, Raj K.

, p. 2825 - 2829 (2007/10/02)

The continuation of studies on the synthesis of side-chain analogues of Δ6a,10a-tetrahydrocannabinol as potential therapeutic agents has led to the syntheses of a possible metabolite 1-hydroxy-6,6,9-trimethyl-7,8,9,10-tetrahydro-6H-dibenzopyran-3-ylacetic acid (1) and 2-(1-hydroxy-6,6,9-trimethyl-7,8,9,10-tetrahydro-6H-dibenzopyran-3-yl)pent-4-ynoic acid (17c).The Pechmann condensation of ethyl 4-methyl-2-oxocyclohexane-1-carboxylate with methyl 3,5-dihydroxyphenylacetate (11), followed by Grignard reaction, was utilized to produce the pyran (1).The key step in the synthesis of the propargylacetic acid (17c) was propargylation of the malonate (15) under phase-transfer catalysis.

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