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S-Chloroacetyl-p-mercaptotoluene, with the molecular formula C9H9ClOS, is an organochlorine compound that serves as a crucial intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. Characterized by its white to light yellow crystalline solid appearance and a melting point of 65-68°C, this acetylating agent is renowned for its reactivity with thiols, leading to the formation of stable thioesters. Its utility extends to the field of chemical biology, where it acts as a biochemical tool for the modification of proteins and peptides. Furthermore, it is a significant building block in the production of agrochemicals and pharmaceuticals, highlighting its importance in organic chemistry due to its versatile reactivity and broad applications.

24197-66-8

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24197-66-8 Usage

Uses

Used in Pharmaceutical Synthesis:
S-Chloroacetyl-p-mercaptotoluene is used as an intermediate in the synthesis of various pharmaceuticals for its ability to form stable thioesters with thiols, which is crucial in the development of new drug molecules.
Used in Dye Production:
In the dye industry, S-Chloroacetyl-p-mercaptotoluene is utilized as a key intermediate, contributing to the creation of diverse dyes with specific color properties.
Used in Chemical Biology:
S-Chloroacetyl-p-mercaptotoluene is employed as a biochemical tool in chemical biology for the modification of proteins and peptides, enabling researchers to study protein functions and interactions in a controlled manner.
Used in Agrochemical Production:
S-CHLOROACETYL-P-MERCAPTOTOLUENE is used as an important building block in the production of agrochemicals, playing a vital role in the development of effective and targeted agricultural products.
Used in Organic Chemistry Research:
Due to its versatile reactivity, S-Chloroacetyl-p-mercaptotoluene is a valuable chemical in the field of organic chemistry, aiding researchers in exploring new reactions and synthesizing novel organic compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 24197-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,9 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 24197-66:
(7*2)+(6*4)+(5*1)+(4*9)+(3*7)+(2*6)+(1*6)=118
118 % 10 = 8
So 24197-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClOS/c1-7-2-4-8(5-3-7)12-9(11)6-10/h2-5H,6H2,1H3

24197-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name S-(4-methylphenyl) 2-chloroethanethioate

1.2 Other means of identification

Product number -
Other names S-chloroacetyl-p-mercaptotoluene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24197-66-8 SDS

24197-66-8Relevant academic research and scientific papers

Silica-promoted facile synthesis of thioesters and thioethers: A highly efficient, reusable and environmentally safe solid support

Basu, Basudeb,Paul, Susmita,Nanda, Ashis K.

experimental part, p. 767 - 771 (2010/09/05)

An efficient, mild and rapid procedure for the acylation and alkylation of aromatic and aliphatic thiols mediated on a silica gel surface at room temperature is described. The protocol allows the protection of thiols under neutral heterogeneous conditions without requiring any bases or Lewis acids, and the silica gel used as the promoter can be recycled for several runs without any loss of activity.

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