243645-06-9Relevant academic research and scientific papers
Synthesis and applications of fluorous silyl protecting groups with improved acid stability
Roever, Stephan,Wipf, Peter
, p. 5667 - 5670 (2007/10/03)
Fluorous alkoxysilyl protecting groups have been developed and evaluated for their acid stability. tert-Butylphenyl-1H,1H,2H,2H-heptadecafluorodecyloxysilyl (BPFOS) ethers in particular were found to be surprisingly acid stable and allow simple protection-purification-deprotection schemes by liquid-liquid extraction with FC-72/CH3CN or by solid phase extraction with fluorous reverse phase silica gel.
