24377-48-8

Usage

Uses

Used in Pharmaceutical Industry:
20-(piperidin-1-ylmethylidene)pregn-4-en-3-one is used as a pharmaceutical candidate for the development of new drugs for hormone-related conditions due to its unique and complex chemical structure and potential applications in the treatment of gynecological and endocrine disorders.
Used in Medicinal Chemistry Research:
20-(piperidin-1-ylmethylidene)pregn-4-en-3-one is used as a research compound for further exploration and development in the field of medicinal chemistry, with the aim of discovering its potential applications and optimizing its properties for therapeutic use.

Upstream product

• 4030-92-6 24β-methylcholesta-4,22E-dien-3-one 
• 2981-10-4 1-(cyclohex-1-en-1-yl)piperidine 
• 24254-01-1 20β-carboxyaldehyde-4-pregnen-3-one 
• 60966-36-1 (20S)-21-hydroxy-20-methylpregn-4-en-3-one 
• 110-89-4 piperidine 
• 1614-92-2 1-(N-piperidino)cyclopentene 
• 3986-89-8 (20S)-3-oxopregn-4-ene-20-carboxaldehyde 

Downstream Products

• 120854-36-6 1-butyl-1-(3-oxo-23,24-dinor-chola-4,20-dien-21-ξ-yl)-piperidinium; bromide 
• 123885-33-6 1-methyl-1-(3-oxo-23,24-dinor-chola-4,20-dien-21-ξ-yl)-piperidinium; iodide 
• 103128-71-8 20-bromo-3-oxo-23,24-dinor-20ξH-chol-4-en-21-al 
• 57-83-0 Progesterone 
• 50323-70-1 3-oxo-23,24-dinor-chola-4,17(20)ξ-dien-21-al 
• 24254-01-1 20β-carboxyaldehyde-4-pregnen-3-one 

Relevant academic research and scientific papers

High-efficiency low-pollution preparation method for progesterone

The invention discloses a high-efficiency low-pollution preparation method of progesterone, and belongs to the technical fields of preparation and processing of steroid hormone drugs. According to themethod, 21-hydroxy-20-methylpregn-4-en-3-one is used as a starting raw material, a TEMPO-NaClO reagent is used for oxidation to form an aldehyde, enamination is performed, and copper catalytic oxidation degradation is performed to prepare the progesterone. The preparation method of the progesterone provided by the invention has the advantages that the raw materials and reagents are cheap and easyto obtain, and the market competitiveness in equipment investment and production cost is extremely high; the reaction is mild and safe, and the operation is easy to control; the reaction yield is high, and purification is simple and convenient; and the used reagents are low in environmental pollution, particularly chromium-containing high-pollution reagents are not used, so that the method conforms to the industrial development trend of green chemistry and has good economic and social benefits.