244168-28-3

Basic information

• Product Name: 4-methylphenylsulfonamido-N-methoxy-N-methylacetamide
• Synonyms: 4-methylphenylsulfonamido-N-methoxy-N-methylacetamide
• CAS NO: 244168-28-3
• Molecular Weight: 272.325
• Mol File: 244168-28-3.mol

Chemical Properties

• CAS DataBase Reference: 4-methylphenylsulfonamido-N-methoxy-N-methylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylphenylsulfonamido-N-methoxy-N-methylacetamide(244168-28-3)
• EPA Substance Registry System: 4-methylphenylsulfonamido-N-methoxy-N-methylacetamide(244168-28-3)

Safety Data

• Hazardous Substances Data: 244168-28-3(Hazardous Substances Data)

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 1080-44-0 N-Tosylglycine 
• 2645-02-5 methyl tosylglycinate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 918954-49-1 4-methyl-N-(2-oxobutyl)benzenesulfonamide 
• 54972-26-8 N-(4-methylbenzenesulphonyl)propanamin-2-one 
• 30057-92-2 N-(p-toluenesulfonyl)aminoacetophenone 

Relevant articles and documents

Convenient conversion of acid to Weinreb's amide

Various carboxylic acids are converted to their corresponding N-methoxy- N-methyl amides through tile mixed anhydride formed by their reaction with pivaloyl chloride.

Chiral Br?nsted Acid Catalyzed Enantioselective Dehydrative Nazarov-Type Electrocyclization of Aryl and 2-Thienyl Vinyl Alcohols

An efficient chiral Br?nsted acid-catalyzed enantioselective dehydrative Nazarov-type electrocyclization (DNE) of electron-rich aryl- and 2-thienyl-β-amino-2-en-1-ols is described. The 4π conrotatory electrocyclization reaction affords access to a wide variety of the corresponding 1H-indenes and 4H-cyclopenta[b]thiophenes in excellent yields of up to 99% and enantiomeric excess (ee) values of up to 99%. Experimental and computational studies based on a proposed intimate contact ion-pair species that is further assisted by hydrogen bonding between the amino group of the substrate cation and chiral catalyst anion provide insight into the observed product enantioselectivities.

Gold-Catalyzed Aminoalkenylation of β-Amino-1,n-Diynols to Cycloalkyl-, Piperidinyl- and Pyranyl-Fused Pyrroles

A synthetic method to prepare cycloalkyl-, piperidinyl- and pyranyl-fused pyrroles efficiently by gold(I)-catalyzed dehydrative aminoalkenylation of β-amino-1,n-diynols under mild conditions at room temperature is described.

Diastereoselective cycloaddition of alkylidenecyclopropane nitrones from palladium(0)-catalyzed nucleophilic substitution of asymmetric 1-alkenylcyclopropyl esters by amino acids

The asymmetric construction of perhydropyrrolo[3,4-b]pyridine derivatives was performed by chemo- and regioselective formation of enantiopure alkylidenecyclopropane nitrones, followed by diastereoselective intramolecular 1,3-dipolar cycloaddition. The res