244229-56-9

Upstream product

• 244126-23-6 toluene-4-sulfonic acid 5-bromo-2-hydroxy-3-methyl-phenyl ester 
• 244126-22-5 toluene-4-sulfonic acid 2-hydroxy-3-methyl-phenyl ester 
• 488-17-5 3-methylbenzene-1,2-diol 
• 244126-24-7 toluene-4-sulfonic acid 5-bromo-2-methoxy-3-methyl-phenyl ester 

Downstream Products

• 442663-55-0 3-benzyloxy-11-[1-(6-benzyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-2-hydroxy-ethyl]-12-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxy-5-methyl-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-56-1 nitrile compound 
• 442663-57-2 C₅₀H₅₈Cl₃N₃O₁₀Si 
• 442663-29-8 (2-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-phenyl)-1-{[2-(tert-butyl-diphenyl-silanyloxy)-1-(6-methoxymethoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-[1-(4-methoxy-phenylcarbamoyl)-ethyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 244126-35-0 (1R,9S,10R,11R,12R)-12-Azido-6-bromo-3,4-dimethoxy-5-methyl-13-(toluene-4-sulfonyl)-13-aza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-triene-10,11-diol 
• 244126-38-3 C₂₄H₂₅BrN₂O₇S 
• 244126-36-1 (1R,9S,10R,11R,12R)-12-Amino-6-bromo-3,4-dimethoxy-5-methyl-13-(toluene-4-sulfonyl)-13-aza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-triene-10,11-diol 
• 442663-53-8 silanylether 
• 442663-35-6 (3R,5R,6R,12S,12aS)-2,2,2-trichloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 442663-48-1 Acetic acid (R)-2-{[(S)-3-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-phenyl)-2-tert-butoxycarbonylamino-propionyl]-[1-(4-methoxy-phenylcarbamoyl)-ethyl]-amino}-2-(6-methoxymethoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl ester 
• 442663-58-3 alcohol compound 
• 442663-36-7 (1R,9S,10R,12R)-11-[(R)-2-Acetoxy-1-(6-benzyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-10-cyano-12-formyl-4-methoxy-5-methyl-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-47-0 alcohol 
• 442663-54-9 3-benzyloxy-12-(tert-butyl-dimethyl-silanyloxymethyl)-11-[2-hydroxy-1-(6-hydroxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-4-methoxy-5-methyl-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 

Relevant academic research and scientific papers

Total synthesis of ecteinascidin 743

The total synthesis of ecteinascidin 743 (1), an extremely potent antitumor agent, has been accomplished. The synthesis features Ugi's 4CC reaction, intramolecular Heck reaction, phenol-aldehyde cyclization, and acid-induced intramolecular sulfide formation. Copyright

Synthetic study on ecteinascidin 743 starting from D-glucose

During the course of synthetic study on ecteinascidin 743 (1), key intermediate 5 was prepared. Stereocontrolled synthesis of 5 from D-glucose was accomplished using incorporation of two nitrogen atoms and stereoselective addition of a phenol to an imine