442663-57-2

Upstream product

• 442663-29-8 (2-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-phenyl)-1-{[2-(tert-butyl-diphenyl-silanyloxy)-1-(6-methoxymethoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-[1-(4-methoxy-phenylcarbamoyl)-ethyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 442663-55-0 3-benzyloxy-11-[1-(6-benzyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-2-hydroxy-ethyl]-12-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxy-5-methyl-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-53-8 silanylether 
• 442663-35-6 (3R,5R,6R,12S,12aS)-2,2,2-trichloroethyl 7-(benzyloxy)-3-[6-(benzyloxy)-7-methylbenzo[d][1,3]dioxol-4-yl]-5-{[(tert-butyldimethylsilyl)oxy]methyl}-8-methoxy-9-methyl-3,5,6,11,12,12a-hexahydro-2H-6,12-epiminobenzo[e]oxazolo[3,2-a]azocine-13-carboxylate 
• 442663-48-1 Acetic acid (R)-2-{[(S)-3-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-phenyl)-2-tert-butoxycarbonylamino-propionyl]-[1-(4-methoxy-phenylcarbamoyl)-ethyl]-amino}-2-(6-methoxymethoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl ester 
• 442663-47-0 alcohol 
• 442663-54-9 3-benzyloxy-12-(tert-butyl-dimethyl-silanyloxymethyl)-11-[2-hydroxy-1-(6-hydroxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-4-methoxy-5-methyl-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-34-5 (1R,9S,12R)-11-[(R)-2-Acetoxy-1-(6-acetoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-12-hydroxymethyl-4-methoxy-5-methyl-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-52-7 (1R,9S)-11-[(R)-2-Acetoxy-1-(6-acetoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-4-methoxy-5-methyl-12-methylene-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-50-5 (S)-4-[(R)-2-Acetoxy-1-(6-methanesulfonyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-2-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-benzyl)-5-methyl-3,6-dioxo-piperazine-1-carboxylic acid tert-butyl ester 
• 442663-31-2 4-[2-acetoxy-1-(6-methanesulfonyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-2-(3-benzyloxy-2-iodo-4-methoxy-5-methyl-benzyl)-5-methyl-3-oxo-3,4-dihydro-2H-pyrazine-1-carboxylic acid tert-butyl ester 
• 442663-32-3 (1R,9S)-11-[(R)-2-Acetoxy-1-(6-methanesulfonyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-4-methoxy-5-methyl-12-methylene-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid tert-butyl ester 
• 442663-51-6 (1R,9S)-11-[(R)-2-Acetoxy-1-(6-acetoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-4-methoxy-5-methyl-12-methylene-10-oxo-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid tert-butyl ester 
• 442663-49-2 mecyl body 

Downstream Products

• 114899-77-3 ecteinascidin 743 
• 114899-80-8 (1'R,6R,6aR,7R,13S,14R,16R)-5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8-dihydroxy-7',9-dimethoxy-4,10,23-trimethyl-19-oxo-spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinoline]-14-carbonitrile 
• 442663-36-7 (1R,9S,10R,12R)-11-[(R)-2-Acetoxy-1-(6-benzyloxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-3-benzyloxy-10-cyano-12-formyl-4-methoxy-5-methyl-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2,4,6-triene-13-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 442663-58-3 alcohol compound 

Relevant academic research and scientific papers

Total synthesis of ecteinascidin 743

The total synthesis of ecteinascidin 743 (1), an extremely potent antitumor agent, has been accomplished. The synthesis features Ugi's 4CC reaction, intramolecular Heck reaction, phenol-aldehyde cyclization, and acid-induced intramolecular sulfide formation. Copyright